U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CBL8 calcineurin B-like protein 8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842756, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CBL8
Official Full Name
calcineurin B-like protein 8
Primary source
TAIR:AT1G64480
Locus tag
AT1G64480
See related
Araport:AT1G64480
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
calcineurin B-like protein 8; F1N19.5; F1N19_5
Summary
calcineurin B-like protein 8, member of plant-specific family of calcium sensor proteins containing 3 EF-hand motifs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CBL8 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (23947794..23950361, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Glycine-rich protein family Neighboring gene collagen triple helix protein Neighboring gene phosphatidylinositol 4-kinase gamma-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DEK, chromatin associated protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Calmodulins and calcineurin B-like proteins: calcium sensors for specific signal response coupling in plants. Luan S, et al. Plant Cell, 2002. PMID 12045290, Free PMC Article
  2. CBL-mediated targeting of CIPKs facilitates the decoding of calcium signals emanating from distinct cellular stores. Batistic O, et al. Plant J, 2010 Jan. PMID 19832944
  3. A protein kinase, calcineurin B-like protein-interacting protein Kinase9, interacts with calcium sensor calcineurin B-like Protein3 and regulates potassium homeostasis under low-potassium stress in Arabidopsis. Liu LL, et al. Plant Physiol, 2013 Jan. PMID 23109687, Free PMC Article
  4. Phosphorylation of calcineurin B-like (CBL) calcium sensor proteins by their CBL-interacting protein kinases (CIPKs) is required for full activity of CBL-CIPK complexes toward their target proteins. Hashimoto K, et al. J Biol Chem, 2012 Mar 9. PMID 22253446, Free PMC Article
  5. The NAF domain defines a novel protein-protein interaction module conserved in Ca2+-regulated kinases. Albrecht V, et al. EMBO J, 2001 Mar 1. PMID 11230129, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables kinase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcium-mediated signaling TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
calcineurin B-like protein 8
NP_001319319.1
  • calcineurin B-like protein 8 (CBL8); CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), Calcineurin B protein (InterPro:IPR015757), Recoverin (InterPro:IPR001125), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand-like domain (InterPro:IPR011992), EF-hand (InterPro:IPR018248), EF-HAND 2 (InterPro:IPR018249); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT5G24270.2); Has 8036 Blast hits to 8016 proteins in 760 species: Archae - 0; Bacteria - 12; Metazoa - 3984; Fungi - 1032; Plants - 1911; Viruses - 0; Other Eukaryotes - 1097 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23947794..23950361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001334162.1 → NP_001319319.1  calcineurin B-like protein 8 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FUQ7, Q9SGW7
    UniProtKB/TrEMBL
    A0A178W4X2, A0A384KGE1, Q0V872
    Conserved Domains (1) summary
    COG5126
    Location:29 → 187
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. NM_001334163.1 → NP_001322653.1  calcineurin B-like protein 8 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FUQ7, Q9SGW7
    UniProtKB/TrEMBL
    A0A178W4X2, A0A384KGE1, Q0V872
    Conserved Domains (1) summary
    COG5126
    Location:29 → 187
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  3. NM_105123.2 → NP_176629.1  calcineurin B-like protein 8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176629.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FUQ7, Q9SGW7
    UniProtKB/TrEMBL
    A0A178W4X2, A0A384KGE1, Q0V872
    Conserved Domains (1) summary
    COG5126
    Location:29 → 187
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  4. NM_001334164.1 → NP_001322654.1  calcineurin B-like protein 8 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W6J9, A0A1P8AUP2, A0A384KNV3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FUQ7.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools