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HT1 Protein kinase superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842538, updated on 18-Sep-2024

Summary

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Official Symbol
HT1
Official Full Name
Protein kinase superfamily protein
Primary source
TAIR:AT1G62400
Locus tag
AT1G62400
See related
Araport:AT1G62400
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F24O1.13; F24O1_13; high leaf temperature 1
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Genomic context

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See HT1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (23089610..23091732)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ACC oxidase 2 Neighboring gene Octicosapeptide/Phox/Bem1p (PB1) domain-containing protein / tetratricopeptide repeat (TPR)-containing protein Neighboring gene MIF4G domain-containing protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dominant and recessive mutations in the Raf-like kinase HT1 gene completely disrupt stomatal responses to CO2 in Arabidopsis. Hashimoto-Sugimoto M, et al. J Exp Bot, 2016 May. PMID 27034327, Free PMC Article
  2. The HT1 protein kinase is essential for red light-induced stomatal opening and genetically interacts with OST1 in red light and CO2 -induced stomatal movement responses. Matrosova A, et al. New Phytol, 2015 Dec. PMID 26192339
  3. Arabidopsis HT1 kinase controls stomatal movements in response to CO2. Hashimoto M, et al. Nat Cell Biol, 2006 Apr. PMID 16518390
  4. Natural Variation in Arabidopsis Cvi-0 Accession Reveals an Important Role of MPK12 in Guard Cell CO2 Signaling. Jakobson L, et al. PLoS Biol, 2016 Dec. PMID 27923039, Free PMC Article
  5. A Dominant Mutation in the HT1 Kinase Uncovers Roles of MAP Kinases and GHR1 in CO2-Induced Stomatal Closure. Hõrak H, et al. Plant Cell, 2016 Oct. PMID 27694184, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Both the loss-of-function and gain-of-function ht1 mutants have completely disrupted CO2 responses, although they have normal responses to ABA. Light-induced stomatal opening is smaller in ht1-3 allele and much smaller in ht1-2. The results indicate that HT1 is a critical regulator for CO2 signaling and is partially involved in the light-induced stomatal opening pathway.
    Title: Dominant and recessive mutations in the Raf-like kinase HT1 gene completely disrupt stomatal responses to CO2 in Arabidopsis.
  2. Study propose a model for sequential roles of MPK12, HT1, and GHR1 in the ABA-independent regulation of SLAC1 during CO2-induced stomatal closure.
    Title: A Dominant Mutation in the HT1 Kinase Uncovers Roles of MAP Kinases and GHR1 in CO2-Induced Stomatal Closure.
  3. These results demonstrate that HT1 is essential for red light-induced stomatal opening and interacts genetically with OST1 during stomatal responses to red light and altered [CO2 ].
    Title: The HT1 protein kinase is essential for red light-induced stomatal opening and genetically interacts with OST1 in red light and CO2 -induced stomatal movement responses.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_104920.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein serine/threonine/tyrosine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cellular response to carbon dioxide IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to carbon dioxide IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein autophosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of response to red or far red light IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of stomatal closure IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of stomatal movement IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Protein kinase superfamily protein
NP_176430.2
  • high leaf temperature 1 (HT1); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT5G58950.1); Has 132835 Blast hits to 130849 proteins in 5233 species: Archae - 136; Bacteria - 14325; Metazoa - 51137; Fungi - 12092; Plants - 33829; Viruses - 555; Other Eukaryotes - 20761 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23089610..23091732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104920.3 → NP_176430.2  Protein kinase superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4HYS2, Q2MHE4, Q9MAV2
    UniProtKB/TrEMBL
    A0A178W8M6, A0A5S9WRF7
    Conserved Domains (1) summary
    cd13999
    Location:93 → 340
    STKc_MAP3K-like; Catalytic domain of Mitogen-Activated Protein Kinase (MAPK) Kinase Kinase-like Serine/Threonine kinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2MHE4.1

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