U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842462, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Primary source
TAIR:AT1G61660
Locus tag
AT1G61660
See related
Araport:AT1G61660
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T13M11.1; T13M11_1
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (22753611..22756387, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene miscRNA Neighboring gene serine protease, putative (Protein of unknown function, DUF538) Neighboring gene Lung seven transmembrane receptor family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The function of OsbHLH068 is partially redundant with its homolog, AtbHLH112, in the regulation of the salt stress response but has opposite functions to control flowering in Arabidopsis. Chen HC, et al. Plant Mol Biol, 2017 Jul. PMID 28631168, Free PMC Article
  2. Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs. Liu Y, et al. New Phytol, 2015 Aug. PMID 25827016
  3. A stele-enriched gene regulatory network in the Arabidopsis root. Brady SM, et al. Mol Syst Biol, 2011 Jan 18. PMID 21245844, Free PMC Article
  4. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534
  5. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results suggested that the rice gene HLH068 and the Arabidopsis gene HLH112 share partially redundant functions in the regulation of abiotic stress responses but have opposite functions to control flowering in Arabidopsis.[HLH112]
    Title: The function of OsbHLH068 is partially redundant with its homolog, AtbHLH112, in the regulation of the salt stress response but has opposite functions to control flowering in Arabidopsis.
  2. the functional role of a basic helix-loop-helix transcription factor from Arabidopsis, AtbHLH112, in response to abiotic stress, was investigated.
    Title: Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001198355.1
NM_001198356.1
NM_001333995.1
NM_001333996.1
NM_001333997.1
NM_104847.4
NM_179505.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to abscisic acid stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within cellular response to salt stress IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within cellular response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of proline metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NP_001185284.1
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G20640.1).
NP_001185285.1
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G20640.1).
NP_564782.1
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G20640.1); Has 1502 Blast hits to 1260 proteins in 110 species: Archae - 0; Bacteria - 97; Metazoa - 123; Fungi - 48; Plants - 982; Viruses - 0; Other Eukaryotes - 252 (source: NCBI BLink).
NP_849836.1
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G20640.1); Has 1462 Blast hits to 1215 proteins in 108 species: Archae - 0; Bacteria - 95; Metazoa - 127; Fungi - 44; Plants - 947; Viruses - 0; Other Eukaryotes - 249 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    22753611..22756387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104847.4 → NP_564782.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564782.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3ECK8, Q8LE61, Q94JL3, Q9SYA1
    UniProtKB/TrEMBL
    A0A178WKI7, A0A5S9WNE5, A0A7G2E2B7
    Conserved Domains (1) summary
    cd11393
    Location:276 → 327
    bHLH_AtbHLH_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins

  2. NM_001333996.1 → NP_001322873.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WMC9, A0A7G2E2B7
    Conserved Domains (1) summary
    cd11393
    Location:276 → 327
    bHLH_AtbHLH_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins

  3. NM_001333995.1 → NP_001322871.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AVD6

  4. NM_001333997.1 → NP_001322872.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3ECK8, Q8LE61, Q94JL3, Q9SYA1
    UniProtKB/TrEMBL
    A0A178WKI7, A0A5S9WNE5, A0A7G2E2B7
    Conserved Domains (1) summary
    cd11393
    Location:276 → 327
    bHLH_AtbHLH_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins

  5. NM_179505.1 → NP_849836.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849836.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WMC9, A0A7G2E2B7
    Conserved Domains (1) summary
    cd11393
    Location:276 → 327
    bHLH_AtbHLH_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins

  6. NM_001198355.1 → NP_001185284.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001185284.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2E2B7, F4HVD9
    Conserved Domains (1) summary
    smart00353
    Location:277 → 320
    HLH; helix loop helix domain

  7. NM_001198356.1 → NP_001185285.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001185285.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2E2B7, F4HVE0
    Conserved Domains (1) summary
    smart00353
    Location:273 → 301
    HLH; helix loop helix domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94JL3.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools