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GolS2 galactinol synthase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842114, updated on 18-Sep-2024

Summary

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Official Symbol
GolS2
Official Full Name
galactinol synthase 2
Primary source
TAIR:AT1G56600
Locus tag
AT1G56600
See related
Araport:AT1G56600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtGolS2; F25P12.95; F25P12_95; galactinol synthase 2
Summary
GolS2 is a galactinol synthase that catalyzes the formation of galactinol from UDP-galactose and myo-inositol. GolS2 transcript levels rise in response to methyl viologen, an oxidative damage-inducing agent. Plants over-expressing GolS2 have increased tolerance to salt, chilling, and high-light stress.
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Genomic context

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See GolS2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (21207537..21209635)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene plant/protein (Protein of unknown function, DUF538) Neighboring gene Clathrin adaptor complexes medium subunit family protein Neighboring gene pseudo Neighboring gene Protein with RNI-like/FBD-like domain Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis galactinol synthase AtGolS2 improves drought tolerance in the monocot model Brachypodium distachyon. Himuro Y, et al. J Plant Physiol, 2014 Aug 15. PMID 24973584
  2. Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis. Song C, et al. Mol Cells, 2016 Jun 30. PMID 27109422, Free PMC Article
  3. Important roles of drought- and cold-inducible genes for galactinol synthase in stress tolerance in Arabidopsis thaliana. Taji T, et al. Plant J, 2002 Feb. PMID 11846875
  4. Metabolic pathways involved in cold acclimation identified by integrated analysis of metabolites and transcripts regulated by DREB1A and DREB2A. Maruyama K, et al. Plant Physiol, 2009 Aug. PMID 19502356, Free PMC Article
  5. Galactinol and raffinose constitute a novel function to protect plants from oxidative damage. Nishizawa A, et al. Plant Physiol, 2008 Jul. PMID 18502973, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Findings provide evidence that GolS1 and GolS2 are directly regulated by HsfA3 and that GolS enzymes play an important role in improving oxidative stress tolerance by increasing galactinol biosynthesis in Arabidopsis.
    Title: Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
  2. AtGolS2 can confer drought tolerance to monocots.
    Title: Arabidopsis galactinol synthase AtGolS2 improves drought tolerance in the monocot model Brachypodium distachyon.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_104537.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables inositol 3-alpha-galactosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within galactose metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to abscisic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to cold IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to salt stress IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
galactinol synthase 2
NP_176053.1
  • galactinol synthase 2 (GolS2); CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 8 (InterPro:IPR002495); BEST Arabidopsis thaliana protein match is: galactinol synthase 3 (TAIR:AT1G09350.1); Has 1296 Blast hits to 1295 proteins in 304 species: Archae - 0; Bacteria - 134; Metazoa - 258; Fungi - 290; Plants - 471; Viruses - 73; Other Eukaryotes - 70 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    21207537..21209635
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104537.3 → NP_176053.1  galactinol synthase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176053.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q945L1, Q9FXB2
    UniProtKB/TrEMBL
    A0A5S9WS80, A0A654EJ40, W8Q3N9
    Conserved Domains (1) summary
    PLN00176
    Location:1 → 335
    PLN00176; galactinol synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FXB2.1

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