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TIM50 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842040, updated on 18-Sep-2024

Summary

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Official Symbol
TIM50
Official Full Name
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
Primary source
TAIR:AT1G55900
Locus tag
AT1G55900
See related
Araport:AT1G55900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
emb1860; EMB1860; embryo defective 1860; F14J16.15; F14J16_15
Summary
component of a translocase in the mitochondrial inner membrane
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Genomic context

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See TIM50 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Sequence:
Chromosome: 1; NC_003070.9 (20903053..20905853)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene Pyridoxal-5'-phosphate-dependent enzyme family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene zinc transporter 11 precursor Neighboring gene zinc ion binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis mitochondrial protein TIM50 affects hypocotyl cell elongation through intracellular ATP level. Kumar S, et al. Plant Sci, 2012 Feb. PMID 22195596
  2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
  3. The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions. Brugière S, et al. Phytochemistry, 2004 Jun. PMID 15276431
  4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
  5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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NM_001198317.1
NM_104467.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
NP_001185246.1
  • TIM50; CONTAINS InterPro DOMAIN/s: NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TAIR:AT1G29780.1).
NP_175986.2
  • TIM50; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: mitochondrion, mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TAIR:AT1G29780.1); Has 2137 Blast hits to 2133 proteins in 243 species: Archae - 0; Bacteria - 8; Metazoa - 726; Fungi - 412; Plants - 369; Viruses - 0; Other Eukaryotes - 622 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20903053..20905853
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001198317.1 → NP_001185246.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001185246.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WKS8, A0A5S9WQA4, F4I3H1
    Conserved Domains (1) summary
    pfam03031
    Location:191 → 338
    NIF; NLI interacting factor-like phosphatase

  2. NM_104467.5 → NP_175986.2  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175986.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q56X01, Q8VYE2, Q9LG22
    UniProtKB/TrEMBL
    A0A178WKS8, A0A5S9WQA4
    Conserved Domains (1) summary
    pfam03031
    Location:191 → 338
    NIF; NLI interacting factor-like phosphatase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VYE2.1

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