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NRPB8A RNA polymerase Rpb8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841866, updated on 18-Sep-2024

Summary

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Official Symbol
NRPB8A
Official Full Name
RNA polymerase Rpb8
Primary source
TAIR:AT1G54250
Locus tag
AT1G54250
See related
Araport:AT1G54250
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATRPABC16.5; F20D21.7; F20D21_7; II AND III 16.5 KDA SUBUNIT; NRPE8A; RNA POLYMERASE I
Summary
One of two highly similar proteins that can serve as non-catalytic subunits of Nuclear RNA polymerases II and V; homologous to budding yeast RPB8. Probably redundant with At3g59600.
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Genomic context

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See NRPB8A in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_003070.9 (20254938..20256688)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Winged helix-turn-helix transcription repressor DNA-binding protein Neighboring gene winged-helix DNA-binding transcription factor family protein Neighboring gene winged-helix DNA-binding transcription factor family protein Neighboring gene eif4a-2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Zhong X, et al. Proc Natl Acad Sci U S A, 2015 Jan 20. PMID 25561521, Free PMC Article
  2. Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II. Ream TS, et al. Mol Cell, 2009 Jan 30. PMID 19110459, Free PMC Article
  3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_104303.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of RNA polymerase II, core complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase V complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
RNA polymerase Rpb8
NP_175827.1
  • NRPB8A; FUNCTIONS IN: DNA-directed RNA polymerase activity; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase II, core complex; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), RNA polymerase, Rpb8 (InterPro:IPR005570); BEST Arabidopsis thaliana protein match is: RNA polymerase Rpb8 (TAIR:AT3G59600.1); Has 513 Blast hits to 511 proteins in 218 species: Archae - 0; Bacteria - 0; Metazoa - 139; Fungi - 205; Plants - 84; Viruses - 0; Other Eukaryotes - 85 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20254938..20256688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104303.3 → NP_175827.1  RNA polymerase Rpb8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175827.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81097
    UniProtKB/TrEMBL
    A0A178VIS0, A0A178WK20, A0A5S9WLR1
    Conserved Domains (1) summary
    pfam03870
    Location:12 → 144
    RNA_pol_Rpb8; RNA polymerase Rpb8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O81097.1

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