WAG1 WAG 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: WAG1
Official Full Name: WAG 1
Primary source: TAIR:AT1G53700
Locus tag: AT1G53700
See related: Araport:AT1G53700
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F22G10.21; F22G10_21; PK3AT; PROTEIN KINASE 3 ARABIDOPSIS THALIANA; WAG 1
Summary: The WAG1 and its homolog, WAG2 each encodes a protein-serine/threonine kinase that are nearly 70% identical to PsPK3 protein. All three together with CsPK3 belong to PsPK3-type kinases. At the N-terminus, all four possess a serine/threonine-rich domain. They are closely related to Arabidopsis kinases PINOID. wag1/wag2 double mutants exhibit a pronounced wavy root phenotype when grown vertically on agar plates (while wild-type plants develop wavy roots only on plates inclined to angles less than 90 degrees), indicating an overlapping role for WAG1 and WAG2 as suppressors of root waving. Simultaneous disruption of PID(AT2G34650) and its 3 closest homologs (PID2/AT2G26700, WAG1/AT1G53700, and WAG2/AT3G14370) abolishes the formation of cotyledons.
NEW: Try the new Gene table
Try the new Transcript table

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

WAG1 is necessary for phytochrome-mediated enhancement of hypocotyl phototropism in Arabidopsis.
Title: PINOID AGC kinases are necessary for phytochrome-mediated enhancement of hypocotyl phototropism in Arabidopsis.
identified the PID homologs WAG1 and WAG2 as new PIN polarity regulators.
Title: Plasma membrane-bound AGC3 kinases phosphorylate PIN auxin carriers at TPRXS(N/S) motifs to direct apical PIN recycling.
wag1 and wag2 are protein kinases that negatively regulate root waving in Arabidopsis. [wag1]
Title: The WAG1 and WAG2 protein kinases negatively regulate root waving in Arabidopsis.

Submit: New GeneRIF Correction

NM_104248.4

Function	Evidence Code	Pubs
enables kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein serine/threonine kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within auxin polar transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cotyledon development	IGI Inferred from Genetic Interaction more info	PubMed
NOT involved_in gravitropism	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

NP_175774.1

WAG 1 (WAG1); CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT3G14370.1); Has 97126 Blast hits to 96120 proteins in 2766 species: Archae - 63; Bacteria - 12090; Metazoa - 36361; Fungi - 11348; Plants - 19901; Viruses - 394; Other Eukaryotes - 16969 (source: NCBI BLink).

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain