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Cytochrome C oxidase copper chaperone (COX17) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841736, updated on 18-Sep-2024

Summary

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Official Full Name
Cytochrome C oxidase copper chaperone (COX17)
Primary source
TAIR:AT1G53030
Locus tag
AT1G53030
See related
Araport:AT1G53030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F8L10.24; F8L10_24
Summary
encodes a copper chaperone, can functional complements the yeast COX17 null mutant. May play a role in the delivery of copper to mitochondria. Expressed in roots and thus may also play a role in copper transport in the roots.
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Genomic context

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Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (19760001..19761496, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ubiquitin-conjugating enzyme family protein Neighboring gene Ubiquitin-conjugating enzyme family protein Neighboring gene uncharacterized protein Neighboring gene tRNA (met) cytidine acetyltransferase, putative (DUF616)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Plant copper chaperones. Wintz H, et al. Biochem Soc Trans, 2002 Aug. PMID 12196180
  2. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
  3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_104181.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper chaperone activity IEA
Inferred from Electronic Annotation
more info
  
enables copper chaperone activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol HDA PubMed 

General protein information

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Preferred Names
Cytochrome C oxidase copper chaperone (COX17)
NP_175711.1
  • Cytochrome C oxidase copper chaperone (COX17); FUNCTIONS IN: copper chaperone activity; INVOLVED IN: copper ion transport; LOCATED IN: mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome c oxidase copper chaperone (InterPro:IPR007745); BEST Arabidopsis thaliana protein match is: cytochrome c oxidase 17 (TAIR:AT3G15352.1); Has 264 Blast hits to 264 proteins in 116 species: Archae - 0; Bacteria - 0; Metazoa - 137; Fungi - 23; Plants - 55; Viruses - 0; Other Eukaryotes - 49 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    19760001..19761496 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104181.5 → NP_175711.1  Cytochrome C oxidase copper chaperone (COX17) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175711.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2HIR2, Q8LFR7, Q94FT1
    UniProtKB/TrEMBL
    A0A178W7R4, A0A5S9WLU5
    Conserved Domains (1) summary
    pfam05051
    Location:27 → 72
    COX17; Cytochrome C oxidase copper chaperone (COX17)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94FT1.1

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