UBP6 ubiquitin-specific protease 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: UBP6
Official Full Name: ubiquitin-specific protease 6
Primary source: TAIR:AT1G51710
Locus tag: AT1G51710
See related: Araport:AT1G51710
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATUBP6; F19C24.8; F19C24_8; ubiquitin-specific protease 6; UBIQUITIN-SPECIFIC PROTEASE 6
Summary: Ubiquitin-specific protease 6 (UBP6). Deubiquinating enzyme. Interacts with calmodulin.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See UBP6 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 17

Sequence:: Chromosome: 1; NC_003070.9 (19175609..19180195, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtUBP6 interacts with calmodulin
Title: Arabidopsis ubiquitin-specific protease 6 (AtUBP6) interacts with calmodulin.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_001084229.1

Supported by ESTs:

NM_104049.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables calmodulin binding	IDA Inferred from Direct Assay more info	PubMed
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables cysteine-type deubiquitinase activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein deubiquitination	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plasmodesma	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: ubiquitin-specific protease 6

NP_001077698.1

ubiquitin-specific protease 6 (UBP6); CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 7 (TAIR:AT3G21280.1); Has 4803 Blast hits to 4486 proteins in 237 species: Archae - 0; Bacteria - 0; Metazoa - 2534; Fungi - 849; Plants - 654; Viruses - 2; Other Eukaryotes - 764 (source: NCBI BLink).

NP_564596.1

ubiquitin-specific protease 6 (UBP6); CONTAINS InterPro DOMAIN/s: Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Ubiquitin conserved site (InterPro:IPR019954), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 7 (TAIR:AT3G21280.1); Has 4793 Blast hits to 4476 proteins in 238 species: Archae - 0; Bacteria - 0; Metazoa - 2508; Fungi - 875; Plants - 657; Viruses - 2; Other Eukaryotes - 751 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

19175609..19180195 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_104049.4 → NP_564596.1 ubiquitin-specific protease 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_564596.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q56ZE7, Q949Y0, Q9C8H9, Q9FPT4

UniProtKB/TrEMBL

A0A178WJ56, A0A5S9WL23, A0A7G2E3S0

Conserved Domains (2) summary

cd02657
Location:105 → 476

Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...

cd16104
Location:1 → 75

Ubl_USP14_like; ubiquitin-like (Ubl) domain found in ubiquitin carboxyl-terminal hydrolase 14 (USP14) and similar proteins
NM_001084229.1 → NP_001077698.1 ubiquitin-specific protease 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001077698.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A7G2E3S0, B3H5V4

Conserved Domains (2) summary

cd02657
Location:66 → 437

Peptidase_C19A; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl ...

pfam00443
Location:65 → 436

UCH; Ubiquitin carboxyl-terminal hydrolase