CH1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CH1
Official Full Name: Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein
Primary source: TAIR:AT1G44446
Locus tag: AT1G44446
See related: Araport:AT1G44446
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA CHLOROPHYLL A OXYGENASE; ATCAO; CAO; CHLORINA 1; CHLOROPHYLL A OXYGENASE; CHLOROPHYLL B SYNTHASE; T18F15.7; T18F15_7
Summary: Encodes chlorophyllide a oxygenase which converts chlorophyllide a to chlorophyllide b by catalyzing two successive hydroxylations at the 7-methyl group of chlorophyllide a . Mutants are deficient in pigments that associate with thylakoid membrane proteins, lacking chlorophyll b and light-harvesting proteins of photosystem II. The protein was shown through cross-linking experiments to interact with Toc75, Toc34, Tic40, Tic20 and Tic22.
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Genomic context

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See CH1 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 8

Sequence:: Chromosome: 1; NC_003070.9 (16848308..16851271, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants.
Title: Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants.
Data indicate that jasmonate biosynthesis was strongly induced in CH1 (At1g44446) mutant plants under high-light stress.
Title: Light-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen.
Determination of a chloroplast degron in the regulatory domain of chlorophyllide a oxygenase.
Title: Determination of a chloroplast degron in the regulatory domain of chlorophyllide a oxygenase.
Data show that the A domain of CAO is essential in the control of chlorophyll biosynthesis and in the survival of seedlings during de-etiolation especially under strong illumination.
Title: Loss of the N-terminal domain of chlorophyllide a oxygenase induces photodamage during greening of Arabidopsis seedlings.
CAO is involved in the regulated import and stabilization of the chlorophyllide b-binding light-harvesting proteins Lhcb1 (LHCII) and Lhcb4 (CP29) in chloroplasts.
Title: A role for chlorophyllide a oxygenase in the regulated import and stabilization of light-harvesting chlorophyll a/b proteins.
The mechanism which regulates Chl a/b ratios and whether the changes in Chl a/b ratios are essential in regulation of LHC accumulation during light acclimation was studied.
Title: Effects of chlorophyllide a oxygenase overexpression on light acclimation in Arabidopsis thaliana.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001333230.1

Supported by ESTs:

NM_103548.5

Supported by ESTs:

NM_202240.2

Supported by ESTs:

NM_202241.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables chlorophyllide a oxygenase activity	IDA Inferred from Direct Assay more info	PubMed
enables chlorophyllide a oxygenase activity	IEA Inferred from Electronic Annotation more info
enables chlorophyllide a oxygenase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables iron ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chlorophyll biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chlorophyll biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in chloroplast inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in thylakoid membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein

NP_175088.1

CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941), Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Pheophorbide a oxygenase (InterPro:IPR013626); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 6355 Blast hits to 6353 proteins in 945 species: Archae - 23; Bacteria - 4238; Metazoa - 95; Fungi - 51; Plants - 426; Viruses - 0; Other Eukaryotes - 1522 (source: NCBI BLink).

NP_973969.1

CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941), Pheophorbide a oxygenase (InterPro:IPR013626); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_973970.1

CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

16848308..16851271 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_103548.5 → NP_175088.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_175088.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0WQP6, Q3ECX2, Q3ECX3, Q9MBA1, Q9SPF2, Q9XJ37

UniProtKB/TrEMBL

A0A178W6L1, A0A5S9WPC9

Conserved Domains (1) summary

PLN02281
Location:1 → 536

PLN02281; chlorophyllide a oxygenase
NM_202241.2 → NP_973970.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973970.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9MBA1

Conserved Domains (2) summary

PLN02281
Location:1 → 386

PLN02281; chlorophyllide a oxygenase

cd04337
Location:204 → 332

Rieske_RO_Alpha_Cao; Cao (chlorophyll a oxygenase) is a rieske non-heme iron-sulfur protein located within the plastid-envelope inner and thylakoid membranes, that catalyzes the conversion of chlorophyllide a to chlorophyllide b. CAO is found not only in plants but also in ...
NM_001333230.1 → NP_001321683.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8ARR2
NM_202240.2 → NP_973969.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973969.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9MBA1

Conserved Domains (3) summary

PLN02281
Location:1 → 511

PLN02281; chlorophyllide a oxygenase

cd04337
Location:204 → 332

Rieske_RO_Alpha_Cao; Cao (chlorophyll a oxygenase) is a rieske non-heme iron-sulfur protein located within the plastid-envelope inner and thylakoid membranes, that catalyzes the conversion of chlorophyllide a to chlorophyllide b. CAO is found not only in plants but also in ...

pfam08417
Location:408 → 480

PaO; Pheophorbide a oxygenase