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SUF4 zinc finger (C2H2 type) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839984, updated on 18-Sep-2024

Summary

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Official Symbol
SUF4
Official Full Name
zinc finger (C2H2 type) family protein
Primary source
TAIR:AT1G30970
Locus tag
AT1G30970
See related
Araport:AT1G30970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F17F8.14; suppressor of FRIGIDA4
Summary
Encodes SUF4 (SUPPRESSOR of FRI 4), a putative zinc-finger-containing transcription factor that is required for delayed flowering in winter-annual Arabidopsis. suf4 mutations strongly suppress the late-flowering phenotype of FRI (FRIGIDA) mutants. suf4 mutants also show reduced H3K4 trimethylation at FLC (FLOWERING LOCUS C), a floral inhibitor. SUF4 may act to specifically recruit a putative histone H3 methyltransferase EFS (EARLY FLOWERING IN SHORT DAYS) and the PAF1-like complex to the FLC locus.
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Genomic context

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See SUF4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Sequence:
Chromosome: 1; NC_003070.9 (11040250..11043773, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene GTP-binding family protein Neighboring gene ncRNA Neighboring gene Plant thionin family protein Neighboring gene Plant thionin family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression. Resentini F, et al. Plant Physiol, 2017 Jan. PMID 27920160, Free PMC Article
  2. SUPPRESSOR OF FRI 4 encodes a nuclear-localized protein that is required for delayed flowering in winter-annual Arabidopsis. Kim SY, et al. Development, 2006 Dec. PMID 17079264
  3. Arabidopsis SEC13B Interacts with Suppressor of Frigida 4 to Repress Flowering. Yang Y, et al. Int J Mol Sci, 2023 Dec 8. PMID 38139079, Free PMC Article
  4. Endopolyploidization and flowering time are antagonistically regulated by checkpoint component MAD1 and immunity modulator MOS1. Bao Z, et al. Nat Commun, 2014 Nov 28. PMID 25429892
  5. SUPPRESSOR OF FRIGIDA4, encoding a C2H2-Type zinc finger protein, represses flowering by transcriptional activation of Arabidopsis FLOWERING LOCUS C. Kim S, et al. Plant Cell, 2006 Nov. PMID 17138694, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Arabidopsis SEC13B Interacts with Suppressor of Frigida 4 to Repress Flowering.
    Title: Arabidopsis SEC13B Interacts with Suppressor of Frigida 4 to Repress Flowering.
  2. MOM1 contributes to the regulation of SUF4 and EC1 gene expression.
    Title: SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression.
  3. SUF4 forms a protein complex with FRI and FRL1 and functions as a transcriptional activator of FLC. [SUF4]
    Title: SUPPRESSOR OF FRIGIDA4, encoding a C2H2-Type zinc finger protein, represses flowering by transcriptional activation of Arabidopsis FLOWERING LOCUS C.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001084165.1
NM_001332933.1
NM_102836.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within epigenetic regulation of gene expression IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within negative regulation of flower development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
zinc finger (C2H2 type) family protein
NP_001077634.1
  • suppressor of FRIGIDA4 (SUF4); FUNCTIONS IN: DNA binding, protein homodimerization activity, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: histone H3-K4 methylation, negative regulation of flower development, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; Has 20927 Blast hits to 14395 proteins in 967 species: Archae - 31; Bacteria - 3069; Metazoa - 8441; Fungi - 3219; Plants - 3230; Viruses - 675; Other Eukaryotes - 2262 (source: NCBI BLink).
NP_564369.1
  • suppressor of FRIGIDA4 (SUF4); CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, BED-type predicted (InterPro:IPR003656), Zinc finger, C2H2-type (InterPro:IPR007087); Has 21249 Blast hits to 14717 proteins in 989 species: Archae - 33; Bacteria - 3114; Metazoa - 8587; Fungi - 3278; Plants - 3255; Viruses - 686; Other Eukaryotes - 2296 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    11040250..11043773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102836.3 → NP_564369.1  zinc finger (C2H2 type) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564369.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I7U0, Q56YA6, Q8LE54, Q94BZ2, Q9C5G0, Q9FYI5
    UniProtKB/TrEMBL
    A0A178W1B6, A0A5S9WIV9
    Conserved Domains (2) summary
    PHA03247
    Location:122 → 312
    PHA03247; large tegument protein UL36; Provisional
    sd00019
    Location:14 → 33
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001332933.1 → NP_001322001.1  zinc finger (C2H2 type) family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W057, A0A1P8ASM0

  3. NM_001084165.1 → NP_001077634.1  zinc finger (C2H2 type) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077634.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W1B6, A0A5S9WIV9
    Conserved Domains (1) summary
    PHA03247
    Location:70 → 260
    PHA03247; large tegument protein UL36; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C5G0.1

Gene LinkOut

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