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VAMP721 vesicle-associated membrane protein 721 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839419, updated on 18-Sep-2024

Summary

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Official Symbol
VAMP721
Official Full Name
vesicle-associated membrane protein 721
Primary source
TAIR:AT1G04750
Locus tag
AT1G04750
See related
Araport:AT1G04750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AT VAMP7B; ATVAMP721; VAMP7B; vesicle-associated membrane protein 721; VESICLE-ASSOCIATED MEMBRANE PROTEIN 7B
Summary
Encodes vesicle-associated membrane protein 7B (VAMP7B, or VAMP721). Required for cell plate formation.
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Genomic context

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See VAMP721 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (1331466..1333651, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene tRNA-Met Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene vesicle-associated membrane protein 726 Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis. Uemura T, et al. Plant Physiol, 2019 Feb. PMID 30545905, Free PMC Article
  2. VAMP721 Conformations Unmask an Extended Motif for K+ Channel Binding and Gating Control. Zhang B, et al. Plant Physiol, 2017 Jan. PMID 27821719, Free PMC Article
  3. SNARE proteins VAMP721 and VAMP722 mediate the post-Golgi trafficking required for auxin-mediated development in Arabidopsis. Zhang L, et al. Plant J, 2021 Oct. PMID 34343378
  4. Arabidopsis R-SNARE proteins VAMP721 and VAMP722 are required for cell plate formation. Zhang L, et al. PLoS One, 2011. PMID 22022536, Free PMC Article
  5. Requirement of vesicle-associated membrane protein 721 and 722 for sustained growth during immune responses in Arabidopsis. Yun HS, et al. Mol Cells, 2013 Jun. PMID 23661365, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A tyrosine phospho-switch within the Longin domain of VAMP721 modulates SNARE functionality.
    Title: A tyrosine phospho-switch within the Longin domain of VAMP721 modulates SNARE functionality.
  2. SNARE proteins VAMP721 and VAMP722 mediate the post-Golgi trafficking required for auxin-mediated development in Arabidopsis.
    Title: SNARE proteins VAMP721 and VAMP722 mediate the post-Golgi trafficking required for auxin-mediated development in Arabidopsis.
  3. Synergy among Exocyst and SNARE Interactions Identifies a Functional Hierarchy in Secretion during Vegetative Growth.
    Title: Synergy among Exocyst and SNARE Interactions Identifies a Functional Hierarchy in Secretion during Vegetative Growth.
  4. CCOAOMT1, a candidate cargo secreted via VAMP721/722 secretory vesicles in Arabidopsis.
    Title: CCOAOMT1, a candidate cargo secreted via VAMP721/722 secretory vesicles in Arabidopsis.
  5. Endoplasmic reticulum stress and immune signalings distinctly control cellular abundance of VAMP721/722.
    Title: Regulation of cellular VAMP721/722 abundance in arabidopsis.
  6. The SYP4-VAMP721 secretory pathway is essential for extracellular defense against powdery mildew fungi.The SYP4-VAMP721 pathway mediates secretion of cell wall-modification enzymes.
    Title: A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis.
  7. The VAMP721 Tyrosine-57 forms the core of an extended K+ channel interaction motif.
    Title: VAMP721 Conformations Unmask an Extended Motif for K+ Channel Binding and Gating Control.
  8. interacts with KAT1 and KC1 K+ channels to moderate K+ current at the plasma membrane
    Title: The Arabidopsis R-SNARE VAMP721 Interacts with KAT1 and KC1 K+ Channels to Moderate K+ Current at the Plasma Membrane.
  9. RPW8.2 is initially carried on VAMP721/722 vesicles, and that VAMP721, and to a much lesser extent VAMP722, are essential for transporting RPW8.2 to the extrahaustorial membrane and for the defense activity of RPW8.2.
    Title: The powdery mildew resistance protein RPW8.2 is carried on VAMP721/722 vesicles to the extrahaustorial membrane of haustorial complexes.
  10. The expression of VAMP721/722 genes whose products drive secretory vesicles to the target plasma membrane, was analyzed.
    Title: Model for regulation of VAMP721/722-mediated secretion: growth vs. stress responses.
Submit: New GeneRIF Correction See all GeneRIFs (12)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001331498.1
NM_001331499.1
NM_001331500.1
NM_100353.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell plate formation involved in plant-type cell wall biogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within protein localization to plasma membrane IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to endoplasmic reticulum stress IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell plate IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endosome TAS
Traceable Author Statement
more info
 PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
located_in plasmodesma HDA PubMed 
located_in vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
vesicle-associated membrane protein 721
NP_001318921.1
  • vesicle-associated membrane protein 721 (VAMP721); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: transport, vesicle-mediated transport; LOCATED IN: endosome, plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Longin (InterPro:IPR010908), Longin-like (InterPro:IPR011012), Synaptobrevin (InterPro:IPR001388); BEST Arabidopsis thaliana protein match is: synaptobrevin-related protein 1 (TAIR:AT2G33120.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_171967.1
  • vesicle-associated membrane protein 721 (VAMP721); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: transport, vesicle-mediated transport; LOCATED IN: endosome, plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Longin (InterPro:IPR010908), Longin-like (InterPro:IPR011012), Synaptobrevin (InterPro:IPR001388); BEST Arabidopsis thaliana protein match is: synaptobrevin-related protein 1 (TAIR:AT2G33120.1); Has 2472 Blast hits to 2471 proteins in 261 species: Archae - 0; Bacteria - 0; Metazoa - 997; Fungi - 453; Plants - 611; Viruses - 0; Other Eukaryotes - 411 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1331466..1333651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100353.4 → NP_171967.1  vesicle-associated membrane protein 721 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171967.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23011, Q9MAS4, Q9ZTW3
    UniProtKB/TrEMBL
    A0A178W204, A0A384KQP8, Q681H0, Q681L9
    Conserved Domains (2) summary
    cd14824
    Location:7 → 121
    Longin; longin domain
    pfam00957
    Location:127 → 195
    Synaptobrevin

  2. NM_001331498.1 → NP_001318921.1  vesicle-associated membrane protein 721 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AS81

  3. NM_001331499.1 → NP_001321868.1  vesicle-associated membrane protein 721 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AS81

  4. NM_001331500.1 → NP_001321867.1  vesicle-associated membrane protein 721 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AS81
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZTW3.1

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