U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TUA4 tubulin alpha-4 chain [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839405, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
TUA4
Official Full Name
tubulin alpha-4 chain
Primary source
TAIR:AT1G04820
Locus tag
AT1G04820
See related
Araport:AT1G04820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F13M7.19; TOR2; TORTIFOLIA 2; tubulin alpha-4 chain
Summary
Encodes an alpha tubulin isoform that is expressed in roots, leaves and flowers.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TUA4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (1356084..1358547, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene glycine-rich protein Neighboring gene 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells. Buschmann H, et al. Plant Cell, 2009 Jul. PMID 19638477, Free PMC Article
  2. Plant gamma-tubulin interacts with alphabeta-tubulin dimers and forms membrane-associated complexes. Dryková D, et al. Plant Cell, 2003 Feb. PMID 12566585, Free PMC Article
  3. The microtubule plus-end tracking proteins SPR1 and EB1b interact to maintain polar cell elongation and directional organ growth in Arabidopsis. Galva C, et al. Plant Cell, 2014 Nov. PMID 25415978, Free PMC Article
  4. Gravity-induced modifications to development in hypocotyls of Arabidopsis tubulin mutants. Matsumoto S, et al. Plant Physiol, 2010 Feb. PMID 20018592, Free PMC Article
  5. The small genome of Arabidopsis contains at least six expressed alpha-tubulin genes. Kopczak SD, et al. Plant Cell, 1992 May. PMID 1498608, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data found that in alpha-tubulin mutant, microtubule dynamicity is reduced and twisting of mutant organs appears to be a higher-order expression of the helical expansion of individual cells.
    Title: Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_100360.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables mRNA binding HDA PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to gravity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule-based process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast stroma HDA PubMed 
located_in cytosol HDA PubMed 
located_in extracellular region HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plant-type cell wall HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
part_of tubulin complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tubulin alpha-4 chain
NP_171974.1
  • tubulin alpha-4 chain (TUA4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: response to cadmium ion, microtubule-based process, cellular response to gravity; LOCATED IN: tubulin complex, cytosol, cell wall, plasma membrane, chloroplast; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Alpha tubulin (InterPro:IPR002452), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin alpha-2 chain (TAIR:AT1G50010.1); Has 22626 Blast hits to 22529 proteins in 4679 species: Archae - 4; Bacteria - 25; Metazoa - 4391; Fungi - 13400; Plants - 1532; Viruses - 0; Other Eukaryotes - 3274 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1356084..1358547 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100360.4 → NP_171974.1  tubulin alpha-4 chain [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171974.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DGT7, P29510, Q0WV25
    UniProtKB/TrEMBL
    A0A178W5L2, A0A5S9SKW7, Q944I2
    Conserved Domains (1) summary
    PLN00221
    Location:1 → 450
    PLN00221; tubulin alpha chain; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B9DGT7.2
Q0WV25.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials