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ARK2 armadillo repeat kinesin 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839306, updated on 18-Sep-2024

Summary

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Official Symbol
ARK2
Official Full Name
armadillo repeat kinesin 2
Primary source
TAIR:AT1G01950
Locus tag
AT1G01950
See related
Araport:AT1G01950
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
Arabidopsis thaliana KINESIN Ungrouped clade; armadillo repeat kinesin 2; AtKINUb; F22M8.8; F22M8_8; gene B
Summary
Encodes a member of the armadillo/beta-catenin repeat kinesin motor family. Mutants have twisted roots due to abnormal cell file rotation; the phenotype is dependent on microtubules.
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Genomic context

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See ARK2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Sequence:
Chromosome: 1; NC_003070.9 (325316..330619)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene SET domain-containing protein Neighboring gene zinc finger protein-like protein Neighboring gene Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene SEC7-like guanine nucleotide exchange family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene FAD-binding Berberine family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Stable ARMADILLO REPEAT KINESIN 2 in light inhibits hypocotyl elongation and facilitates light-induced cortical microtubule reorientation in Arabidopsis. Lan M, et al. J Exp Bot, 2023 Feb 5. PMID 36453983
  2. ARK2 stabilizes the plus-end of microtubules and promotes microtubule bundling in Arabidopsis. Lan M, et al. J Integr Plant Biol, 2023 Jan. PMID 36169006
  3. Armadillo repeat-containing kinesins and a NIMA-related kinase are required for epidermal-cell morphogenesis in Arabidopsis. Sakai T, et al. Plant J, 2008 Jan. PMID 17971038
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Stable ARMADILLO REPEAT KINESIN 2 in light inhibits hypocotyl elongation and facilitates light-induced cortical microtubule reorientation in Arabidopsis.
    Title: Stable ARMADILLO REPEAT KINESIN 2 in light inhibits hypocotyl elongation and facilitates light-induced cortical microtubule reorientation in Arabidopsis.
  2. ARK2 stabilizes the plus-end of microtubules and promotes microtubule bundling in Arabidopsis.
    Title: ARK2 stabilizes the plus-end of microtubules and promotes microtubule bundling in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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NM_001160828.1
NM_001160829.1
NM_001331317.1
NM_100075.8

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
armadillo repeat kinesin 2
NP_001154300.1
  • armadillo repeat kinesin 2 (ARK2); FUNCTIONS IN: microtubule motor activity, binding, ATP binding; INVOLVED IN: root development; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: armadillo repeat kinesin 3 (TAIR:AT1G12430.1); Has 17581 Blast hits to 15249 proteins in 612 species: Archae - 56; Bacteria - 561; Metazoa - 7371; Fungi - 1920; Plants - 2768; Viruses - 17; Other Eukaryotes - 4888 (source: NCBI BLink).
NP_001154301.1
  • armadillo repeat kinesin 2 (ARK2); FUNCTIONS IN: microtubule motor activity, binding, ATP binding; INVOLVED IN: root development; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: armadillo repeat kinesin 3 (TAIR:AT1G12430.1); Has 18598 Blast hits to 15978 proteins in 689 species: Archae - 52; Bacteria - 737; Metazoa - 7861; Fungi - 1903; Plants - 2828; Viruses - 15; Other Eukaryotes - 5202 (source: NCBI BLink).
NP_171697.3
  • armadillo repeat kinesin 2 (ARK2); FUNCTIONS IN: microtubule motor activity, binding, ATP binding; INVOLVED IN: root development; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), Armadillo-type fold (InterPro:IPR016024), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: armadillo repeat kinesin 3 (TAIR:AT1G12430.1); Has 19604 Blast hits to 16795 proteins in 739 species: Archae - 69; Bacteria - 853; Metazoa - 8320; Fungi - 2122; Plants - 2828; Viruses - 22; Other Eukaryotes - 5390 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    325316..330619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100075.8 → NP_171697.3  armadillo repeat kinesin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171697.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9CP40, Q0WMY6, Q9LPC6
    UniProtKB/TrEMBL
    A0A178W9D2, A0A5S9S5Q3, A0A654E657
    Conserved Domains (4) summary
    TIGR01612
    Location:326 → 587
    235kDa-fam; reticulocyte binding/rhoptry protein
    PLN03200
    Location:630 → 749
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:638 → 663
    ARM; armadillo repeat [structural motif]
    pfam00225
    Location:66 → 402
    Kinesin; Kinesin motor domain

  2. NM_001331317.1 → NP_001320318.1  armadillo repeat kinesin 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AMI8, A0A5S9S5Q3, A0A654E657

  3. NM_001160829.1 → NP_001154301.1  armadillo repeat kinesin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154301.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9S5Q3, A0A654E657, F4HU83
    Conserved Domains (6) summary
    cd00020
    Location:653 → 769
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00106
    Location:60 → 400
    KISc; Kinesin motor domain
    pfam00225
    Location:66 → 402
    Kinesin; Kinesin motor domain
    pfam10481
    Location:409 → 593
    CENP-F_N; Cenp-F N-terminal domain
    sd00043
    Location:659 → 684
    ARM; armadillo repeat [structural motif]
    cl19297
    Location:413 → 487
    Dor1; Dor1-like family

  4. NM_001160828.1 → NP_001154300.1  armadillo repeat kinesin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154300.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9S5Q3, A0A654E657, F4HU85
    Conserved Domains (6) summary
    cd00020
    Location:615 → 731
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    cd00106
    Location:60 → 400
    KISc; Kinesin motor domain
    pfam00225
    Location:66 → 402
    Kinesin; Kinesin motor domain
    pfam10481
    Location:409 → 576
    CENP-F_N; Cenp-F N-terminal domain
    sd00043
    Location:621 → 646
    ARM; armadillo repeat [structural motif]
    cl19297
    Location:413 → 487
    Dor1; Dor1-like family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LPC6.2

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