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ABCB12 P-glycoprotein 12 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839282, updated on 18-Sep-2024

Summary

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Official Symbol
ABCB12
Official Full Name
P-glycoprotein 12
Primary source
TAIR:AT1G02530
Locus tag
AT1G02530
See related
Araport:AT1G02530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette B12; P-glycoprotein 12; PGP12; T14P4.14; T14P4_14
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Genomic context

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See ABCB12 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (529679..534677)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Outward rectifying potassium channel protein Neighboring gene P-glycoprotein 11 Neighboring gene uncharacterized protein Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_100134.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
P-glycoprotein 12
NP_171754.1
  • P-glycoprotein 12 (PGP12); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to cyclopentenone; LOCATED IN: integral to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 11 (TAIR:AT1G02520.1); Has 834511 Blast hits to 387558 proteins in 4042 species: Archae - 14726; Bacteria - 649276; Metazoa - 18491; Fungi - 13092; Plants - 9791; Viruses - 35; Other Eukaryotes - 129100 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    529679..534677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001331344.1 → NP_001320752.1  P-glycoprotein 12 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8ANT3
    Conserved Domains (3) summary
    cd03249
    Location:368 → 606
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    COG1132
    Location:27 → 607
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
    cd18578
    Location:695 → 969
    ABC_6TM_Pgp_ABCB1_D2_like; Six-transmembrane helical domain 2 (TMD2) of P-glycoprotein 1 (Pgp) and related proteins

  2. NM_100134.4 → NP_171754.1  P-glycoprotein 12 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171754.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FWX8
    UniProtKB/TrEMBL
    A0A178WBY9, A0A654E664
    Conserved Domains (1) summary
    PTZ00265
    Location:3 → 1267
    PTZ00265; multidrug resistance protein (mdr1); Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FWX8.2

Gene LinkOut

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