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LAP6 Chalcone and stilbene synthase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839280, updated on 18-Sep-2024

Summary

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Official Symbol
LAP6
Official Full Name
Chalcone and stilbene synthase family protein
Primary source
TAIR:AT1G02050
Locus tag
AT1G02050
See related
Araport:AT1G02050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
LESS ADHESIVE POLLEN 6; polyketide synthase A; PSKA; T7I23.4; T7I23_4
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Genomic context

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See LAP6 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (359117..360746, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nitroreductase family protein Neighboring gene C2H2-like zinc finger protein Neighboring gene C2H2-type zinc finger family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene squamosa promoter binding protein-like 8 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana. Kim SS, et al. Plant Cell, 2010 Dec. PMID 21193570, Free PMC Article
  2. LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. Dobritsa AA, et al. Plant Physiol, 2010 Jul. PMID 20442277, Free PMC Article
  3. Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells. Lallemand B, et al. Plant Physiol, 2013 Jun. PMID 23632852, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. At1g02050 interacts and constitutes a part of metabolon localized to the endoplasmic reticulum of tapetum cells.At1g02050 is sporopollenin biosynthetic enzyme.
    Title: Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells.
  2. results show hydroxylated alpha-pyrone polyketide compounds generated by the sequential action of ACOS5 and LAP6/LAP5 are potential and previously unknown sporopollenin precursors
    Title: LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana.
  3. LAP5 and LAP6 are multifunctional enzymes and may play a role in both the synthesis of pollen fatty acids and phenolics found in exine.[LAP6]
    Title: LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_100085.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables tetraketide alpha-pyrone synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in flavonoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pollen exine formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within polyketide biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within sporopollenin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Chalcone and stilbene synthase family protein
NP_171707.1
  • LESS ADHESIVE POLLEN 6 (LAP6); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: phenylpropanoid biosynthetic process, pollen exine formation; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Chalcone/stilbene synthase, N-terminal (InterPro:IPR001099), Thiolase-like (InterPro:IPR016039), Polyketide synthase, type III (InterPro:IPR011141), Thiolase-like, subgroup (InterPro:IPR016038), Chalcone/stilbene synthase, C-terminal (InterPro:IPR012328); BEST Arabidopsis thaliana protein match is: Chalcone and stilbene synthase family protein (TAIR:AT4G00040.1); Has 6482 Blast hits to 6477 proteins in 1606 species: Archae - 0; Bacteria - 2500; Metazoa - 0; Fungi - 67; Plants - 3666; Viruses - 0; Other Eukaryotes - 249 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    359117..360746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100085.4 → NP_171707.1  Chalcone and stilbene synthase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171707.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23674, Q4JNW9
    UniProtKB/TrEMBL
    A0A178WKY7, A0A5S9S5U4, A0A654E665
    Conserved Domains (1) summary
    PLN03169
    Location:5 → 394
    PLN03169; chalcone synthase family protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O23674.1

Gene LinkOut

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