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GLR3.4 glutamate receptor 3.4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839268, updated on 18-Sep-2024

Summary

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Official Symbol
GLR3.4
Official Full Name
glutamate receptor 3.4
Primary source
TAIR:AT1G05200
Locus tag
AT1G05200
See related
Araport:AT1G05200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATGLR3.4; GLUR3; glutamate receptor 3.4; LIGAND-GATED CHANNEL-LIKE PROTEIN PRECURSOR; YUP8H12.19; YUP8H12_19
Summary
Encodes a putative glutamate receptor GLR3 with dual localization in plastid and plasma membrane.
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Genomic context

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See GLR3.4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (1504941..1509152)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene Ribosomal protein L6 family Neighboring gene ncRNA Neighboring gene hexokinase-1 protein Neighboring gene ncRNA Neighboring gene Transmembrane protein 97, Putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
    Title: Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
  2. AtGLR3.4-mediated Ca2+ influx may be involved in the regulation of seed germination under salt stress.
    Title: Glutamate Receptor Homolog3.4 is Involved in Regulation of Seed Germination Under Salt Stress in Arabidopsis.
  3. Data indicate that in roots, GLR3.4 and GLR3.2 were present primarily in the phloem, especially in the vicinity of the sieve plates, and GLR3.3 was expressed in most cells of the growing primary root but was not enriched in the phloem.
    Title: Interacting glutamate receptor-like proteins in Phloem regulate lateral root initiation in Arabidopsis.
  4. The effect of 6 amino acids on the glutamate receptors of A. thaliana, and the role of GLR3.3 and GLR3.4 in the channel mechanisms are reported.
    Title: Glutamate receptor subtypes evidenced by differences in desensitization and dependence on the GLR3.3 and GLR3.4 genes.
  5. AtGLR3.4 in particular and GLRs in general could play an important role in the Ca(2+) -based, fast transmission of environmental stress.
    Title: AtGLR3.4, a glutamate receptor channel-like gene is sensitive to touch and cold.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001035894.1
NM_001331525.1
NM_001331526.1
NM_001331527.1
NM_100398.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables glutamate receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables intracellularly ligand-gated monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ligand-gated monoatomic ion channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in calcium-mediated signaling IDA
Inferred from Direct Assay
more info
 PubMed 
NOT involved_in cellular response to abscisic acid stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to acetate IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to amino acid stimulus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within intracellular calcium ion homeostasis NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within monoatomic ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to light stimulus NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
located_in plastid IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glutamate receptor 3.4
NP_001030971.1
  • glutamate receptor 3.4 (GLR3.4); FUNCTIONS IN: protein binding, intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Glutamate receptor-related (InterPro:IPR015683), GPCR, family 3, gamma-aminobutyric acid receptor, type B (InterPro:IPR002455), Extracellular ligand-binding receptor (InterPro:IPR001828), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.5 (TAIR:AT2G32390.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_172012.2
  • glutamate receptor 3.4 (GLR3.4); FUNCTIONS IN: protein binding, intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Extracellular ligand-binding receptor (InterPro:IPR001828), Glutamate receptor-related (InterPro:IPR015683), GPCR, family 3, gamma-aminobutyric acid receptor, type B (InterPro:IPR002455), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.5 (TAIR:AT2G32390.2); Has 6705 Blast hits to 6546 proteins in 599 species: Archae - 47; Bacteria - 1309; Metazoa - 4441; Fungi - 0; Plants - 637; Viruses - 0; Other Eukaryotes - 271 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1504941..1509152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001331523.1 → NP_001320827.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AP10, A0A5S9SP43
    Conserved Domains (2) summary
    cd19990
    Location:62 → 450
    PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    cl21456
    Location:492 → 807
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  2. NM_001331524.1 → NP_001320829.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WK93, A0A1P8AP36

  3. NM_001035894.1 → NP_001030971.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030971.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23048, Q8GXJ4, Q8LGM9, Q9SWD9
    UniProtKB/TrEMBL
    A0A5S9SP43, A0A654EC03, Q53YX3
    Conserved Domains (3) summary
    cd19990
    Location:62 → 450
    PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    pfam00060
    Location:615 → 869
    Lig_chan; Ligand-gated ion channel
    cl21456
    Location:507 → 591
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  4. NM_001331525.1 → NP_001320828.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WKA8

  5. NM_100398.3 → NP_172012.2  glutamate receptor 3.4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172012.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23048, Q8GXJ4, Q8LGM9, Q9SWD9
    UniProtKB/TrEMBL
    A0A5S9SP43, A0A654EC03, Q53YX3
    Conserved Domains (3) summary
    cd19990
    Location:62 → 450
    PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    pfam00060
    Location:615 → 869
    Lig_chan; Ligand-gated ion channel
    cl21456
    Location:507 → 591
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  6. NM_001331526.1 → NP_001320831.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23048, Q8GXJ4, Q8LGM9, Q9SWD9
    UniProtKB/TrEMBL
    A0A5S9SP43, A0A654EC03, Q53YX3
    Conserved Domains (3) summary
    cd19990
    Location:62 → 450
    PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    pfam00060
    Location:615 → 869
    Lig_chan; Ligand-gated ion channel
    cl21456
    Location:507 → 591
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily

  7. NM_001331527.1 → NP_001320830.1  glutamate receptor 3.4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AP10, A0A5S9SP43
    Conserved Domains (2) summary
    cd19990
    Location:62 → 450
    PBP1_GABAb_receptor_plant; periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants
    cl21456
    Location:492 → 807
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GXJ4.2

Gene LinkOut

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