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ORC6 origin recognition complex protein 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839227, updated on 18-Sep-2024

Summary

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Official Symbol
ORC6
Official Full Name
origin recognition complex protein 6
Primary source
TAIR:AT1G26840
Locus tag
AT1G26840
See related
Araport:AT1G26840
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6; ATORC6; origin recognition complex protein 6; ORIGIN RECOGNITION COMPLEX SUBUNIT 6; T2P11.3; T2P11_3
Summary
Origin Recognition Complex subunit 6. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors.
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Genomic context

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See ORC6 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Sequence:
Chromosome: 1; NC_003070.9 (9298670..9300800)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ribonuclease 3 Neighboring gene cullin 3 Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis transcription factor IIB-related protein BRP4 is involved in the regulation of mitotic cell-cycle progression during male gametogenesis. Qin Z, et al. J Exp Bot, 2014 Jun. PMID 24723406, Free PMC Article
  2. The genes encoding Arabidopsis ORC subunits are E2F targets and the two ORC1 genes are differently expressed in proliferating and endoreplicating cells. Diaz-Trivino S, et al. Nucleic Acids Res, 2005. PMID 16179646, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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NM_102448.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within pollen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  
part_of origin recognition complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
origin recognition complex protein 6
NP_174006.2
  • origin recognition complex protein 6 (ORC6); FUNCTIONS IN: DNA binding; INVOLVED IN: DNA replication; LOCATED IN: origin recognition complex; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Origin recognition complex, subunit 6, metazoa/plant (InterPro:IPR020529), Origin recognition complex, subunit 6 (InterPro:IPR008721); Has 179 Blast hits to 179 proteins in 66 species: Archae - 0; Bacteria - 0; Metazoa - 105; Fungi - 0; Plants - 56; Viruses - 0; Other Eukaryotes - 18 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9298670..9300800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102448.4 → NP_174006.2  origin recognition complex protein 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174006.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q6EWW9, Q9ZVH3
    UniProtKB/TrEMBL
    A0A178WC62, A0A5S9W3Q6, A0A654EDZ6
    Conserved Domains (2) summary
    cd11583
    Location:93 → 187
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
    cl21687
    Location:3 → 92
    Orc6_mid; Middle domain of the origin recognition complex subunit 6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZVH3.2

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