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UPS5 ureide permease 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839185, updated on 18-Sep-2024

Summary

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Official Symbol
UPS5
Official Full Name
ureide permease 5
Primary source
TAIR:AT1G26440
Locus tag
AT1G26440
See related
Araport:AT1G26440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATUPS5; T1K7.19; T1K7_19; ureide permease 5
Summary
uptake assays in yeast mutants indicated this splice variant is a cellular importer for allantoin, uracil and xanthine
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Genomic context

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See UPS5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (9143937..9146106, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene FAD-binding Berberine family protein Neighboring gene tRNA-Asn Neighboring gene Carbohydrate-binding X8 domain superfamily protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ureide Permease 5 (AtUPS5) Connects Cell Compartments Involved in Ureide Metabolism. Lescano I, et al. Plant Physiol, 2020 Mar. PMID 31862838, Free PMC Article
  2. Comparative studies on Ureide Permeases in Arabidopsis thaliana and analysis of two alternative splice variants of AtUPS5. Schmidt A, et al. Planta, 2006 Nov. PMID 16738859
  3. Allantoin accumulation mediated by allantoinase downregulation and transport by Ureide Permease 5 confers salt stress tolerance to Arabidopsis plants. Lescano CI, et al. Plant Mol Biol, 2016 Jul. PMID 27209043
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Ups5 knockout plants under salt stress presented a susceptible phenotype and altered allantoin root-to-shoot content ratios.
    Title: Allantoin accumulation mediated by allantoinase downregulation and transport by Ureide Permease 5 confers salt stress tolerance to Arabidopsis plants.
Submit: New GeneRIF Correction

General gene information

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NM_001036017.1
NM_001332711.1
NM_001332712.1
NM_001332713.1
NM_001332714.1
NM_102407.2
NM_179377.2
NM_202186.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables allantoin:proton symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables uracil transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables xanthine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within allantoin transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within nitrogen compound transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within uracil transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within xanthine transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cell plate IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in secretory vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in trans-Golgi network IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ureide permease 5
NP_001031094.1
  • ureide permease 5 (UPS5); LOCATED IN: endomembrane system; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: ureide permease 2 (TAIR:AT2G03530.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_564246.1
  • ureide permease 5 (UPS5); LOCATED IN: endomembrane system; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: ureide permease 2 (TAIR:AT2G03530.2); Has 249 Blast hits to 246 proteins in 69 species: Archae - 0; Bacteria - 112; Metazoa - 0; Fungi - 0; Plants - 119; Viruses - 0; Other Eukaryotes - 18 (source: NCBI BLink).
NP_849708.1
  • ureide permease 5 (UPS5); FUNCTIONS IN: xanthine transmembrane transporter activity, uracil transmembrane transporter activity, allantoin uptake transmembrane transporter activity; INVOLVED IN: xanthine transport, uracil transport, allantoin transport; LOCATED IN: endomembrane system; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: ureide permease 2 (TAIR:AT2G03530.2); Has 265 Blast hits to 257 proteins in 70 species: Archae - 0; Bacteria - 125; Metazoa - 0; Fungi - 0; Plants - 116; Viruses - 0; Other Eukaryotes - 24 (source: NCBI BLink).
NP_973915.1
  • ureide permease 5 (UPS5); FUNCTIONS IN: xanthine transmembrane transporter activity, uracil transmembrane transporter activity, allantoin uptake transmembrane transporter activity; INVOLVED IN: xanthine transport, uracil transport, allantoin transport; LOCATED IN: endomembrane system; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: ureide permease 2 (TAIR:AT2G03530.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9143937..9146106 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202186.3 → NP_973915.1  ureide permease 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973915.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LBT6, Q93Z75, Q9FZC9
    UniProtKB/TrEMBL
    C0Z2W7
    Conserved Domains (1) summary
    pfam07168
    Location:49 → 404
    Ureide_permease; Ureide permease

  2. NM_001332712.1 → NP_001321599.1  ureide permease 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9VXK9, A0A654ED24

  3. NM_001332711.1 → NP_001321598.1  ureide permease 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WMF5, A0A1P8ARD7

  4. NM_001332714.1 → NP_001321600.1  ureide permease 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WMF5, A0A1P8ARD4

  5. NM_179377.2 → NP_849708.1  ureide permease 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849708.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LBT6, Q93Z75, Q9FZC9
    UniProtKB/TrEMBL
    C0Z2W7
    Conserved Domains (1) summary
    pfam07168
    Location:49 → 404
    Ureide_permease; Ureide permease

  6. NM_001332713.1 → NP_001321601.1  ureide permease 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WMF5, A0A1P8ARD4

  7. NM_102407.2 → NP_564246.1  ureide permease 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564246.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9VXK9, A0A654ED24, F4IE73
    Conserved Domains (1) summary
    pfam07168
    Location:49 → 368
    Ureide_permease; Ureide permease

  8. NM_001036017.1 → NP_001031094.1  ureide permease 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031094.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9VXK9, B9DH85
    Conserved Domains (1) summary
    pfam07168
    Location:49 → 342
    Ureide_permease; Ureide permease
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93Z75.1

Gene LinkOut

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