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CB5-A cytochrome B5 isoform A [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839176, updated on 18-Sep-2024

Summary

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Official Symbol
CB5-A
Official Full Name
cytochrome B5 isoform A
Primary source
TAIR:AT1G26340
Locus tag
AT1G26340
See related
Araport:AT1G26340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS CYTOCHROME B5 ISOFORM A; ATCB5-A; B5 #6; cytochrome B5 isoform A; F28B23.1
Summary
encodes a member of the cytochromes b5 family of proteins that localizes to the outer envelope of the chloroplast. The C-terminal portion of the protein appears to be capable of inserting into a plant microsomal membrane in vitro.
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Genomic context

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See CB5-A in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (9113864..9114977)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc-binding dehydrogenase family protein Neighboring gene DNA binding protein Neighboring gene uncharacterized protein Neighboring gene SPIRAL1-like1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis sucrose transporter SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose. Li Y, et al. Mol Plant, 2012 Sep. PMID 22311778
  2. Functional association of cell death suppressor, Arabidopsis Bax inhibitor-1, with fatty acid 2-hydroxylation through cytochrome b₅. Nagano M, et al. Plant J, 2009 Apr. PMID 19054355
  3. Intracellular sorting of the tail-anchored protein cytochrome b5 in plants: a comparative study using different isoforms from rabbit and Arabidopsis. Maggio C, et al. J Exp Bot, 2007. PMID 17322552
  4. Association of cytochrome b5 with ETR1 ethylene receptor signaling through RTE1 in Arabidopsis. Chang J, et al. Plant J, 2014 Feb. PMID 24635651, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_102398.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables heme binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in chloroplast outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in stromule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
cytochrome B5 isoform A
NP_173958.1
  • cytochrome B5 isoform A (CB5-A); CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: cytochrome B5 isoform B (TAIR:AT2G32720.1); Has 4207 Blast hits to 4178 proteins in 465 species: Archae - 2; Bacteria - 26; Metazoa - 1058; Fungi - 1672; Plants - 799; Viruses - 3; Other Eukaryotes - 647 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9113864..9114977
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102398.3 → NP_173958.1  cytochrome B5 isoform A [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173958.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FDW8
    UniProtKB/TrEMBL
    A0A178WMK3, A0A5S9VZK2
    Conserved Domains (1) summary
    pfam00173
    Location:9 → 81
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FDW8.1

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