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CIB5 cryptochrome-interacting basic-helix-loop-helix 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839167, updated on 18-Sep-2024

Summary

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Official Symbol
CIB5
Official Full Name
cryptochrome-interacting basic-helix-loop-helix 5
Primary source
TAIR:AT1G26260
Locus tag
AT1G26260
See related
Araport:AT1G26260
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cryptochrome-interacting basic-helix-loop-helix 5; F28B23.8; F28B23_8
Summary
Encodes CIB5 (cryptochrome-interacting basic-helix-loop-helix). Related to CIB1 (AT4G34530). CIB5 interacts with CRY2 and forms heterodimer with CIB1 in vitro. Regulates flowering time redundantly with CIB1.
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Genomic context

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See CIB5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (9086804..9089375)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Proline-rich extensin-like family protein Neighboring gene Proline-rich extensin-like family protein Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol 3- and 4-kinase family protein Neighboring gene BSD domain-containing protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Photoexcited CRY2 interacts with CIB1 to regulate transcription and floral initiation in Arabidopsis. Liu H, et al. Science, 2008 Dec 5. PMID 18988809
  2. Multiple bHLH proteins form heterodimers to mediate CRY2-dependent regulation of flowering-time in Arabidopsis. Liu Y, et al. PLoS Genet, 2013. PMID 24130508, Free PMC Article
  3. A central role of Arabidopsis thaliana ovate family proteins in networking and subcellular localization of 3-aa loop extension homeodomain proteins. Hackbusch J, et al. Proc Natl Acad Sci U S A, 2005 Mar 29. PMID 15781858, Free PMC Article
  4. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
  5. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Heim MA, et al. Mol Biol Evol, 2003 May. PMID 12679534

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001036016.2
NM_001332707.1
NM_001332708.1
NM_001332709.1
NM_102390.3
NM_202184.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of flower development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
involved_in response to blue light IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cryptochrome-interacting basic-helix-loop-helix 5
NP_001031093.1
  • cryptochrome-interacting basic-helix-loop-helix 5 (CIB5); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: positive regulation of flower development, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G68920.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_173950.1
  • cryptochrome-interacting basic-helix-loop-helix 5 (CIB5); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: positive regulation of flower development, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G68920.3); Has 2014 Blast hits to 2008 proteins in 104 species: Archae - 0; Bacteria - 3; Metazoa - 32; Fungi - 24; Plants - 1947; Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).
NP_973913.1
  • cryptochrome-interacting basic-helix-loop-helix 5 (CIB5); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: positive regulation of flower development, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G68920.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    9086804..9089375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102390.3 → NP_173950.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173950.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q700E2, Q9C670
    UniProtKB/TrEMBL
    A0A178WLZ9, A0A5S9VWQ4
    Conserved Domains (1) summary
    cd18919
    Location:219 → 304
    bHLH_AtBPE_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BIG PETAL (BPE) and similar proteins

  2. NM_001332707.1 → NP_001323071.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q700E2, Q9C670
    UniProtKB/TrEMBL
    A0A178WLZ9, A0A5S9VWQ4
    Conserved Domains (1) summary
    cd18919
    Location:219 → 304
    bHLH_AtBPE_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BIG PETAL (BPE) and similar proteins

  3. NM_001332708.1 → NP_001323072.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AVX7, A0A5S9VWQ4

  4. NM_001332709.1 → NP_001323073.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q700E2, Q9C670
    UniProtKB/TrEMBL
    A0A178WLZ9, A0A5S9VWQ4
    Conserved Domains (1) summary
    cd18919
    Location:219 → 304
    bHLH_AtBPE_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BIG PETAL (BPE) and similar proteins

  5. NM_202184.3 → NP_973913.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973913.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q700E2, Q9C670
    UniProtKB/TrEMBL
    A0A178WLZ9, A0A5S9VWQ4
    Conserved Domains (1) summary
    cd18919
    Location:219 → 304
    bHLH_AtBPE_like; basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana BIG PETAL (BPE) and similar proteins

  6. NM_001036016.2 → NP_001031093.1  cryptochrome-interacting basic-helix-loop-helix 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031093.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9VWQ4
    Conserved Domains (2) summary
    smart00353
    Location:184 → 233
    HLH; helix loop helix domain
    pfam05093
    Location:121 → 158
    CIAPIN1; Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C670.1

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