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NDT2 NAD+ transporter 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839124, updated on 18-Sep-2024

Summary

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Official Symbol
NDT2
Official Full Name
NAD+ transporter 2
Primary source
TAIR:AT1G25380
Locus tag
AT1G25380
See related
Araport:AT1G25380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA NAD+ TRANSPORTER 2; ATNDT2; F4F7.45; NAD+ transporter 2
Summary
Encodes a mitochondrial-localized NAD+ transporter that transports NAD+ in a counter exchange mode with ADP and AMP in vitro.
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Genomic context

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See NDT2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Sequence:
Chromosome: 1; NC_003070.9 (8903405..8906455)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene hypothetical protein (DUF1639) Neighboring gene Metallo-hydrolase/oxidoreductase superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene miscRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis. Feitosa-Araujo E, et al. Plant Cell Physiol, 2020 May 1. PMID 32065636, Free PMC Article
  2. Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. Palmieri F, et al. J Biol Chem, 2009 Nov 6. PMID 19745225, Free PMC Article
  3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis.
    Title: Downregulation of a Mitochondrial NAD+ Transporter (NDT2) Alters Seed Production and Germination in Arabidopsis.
  2. NDT1 resides in chloroplasts, whereas NDT2 locates to mitochondria.
    Title: Molecular identification and functional characterization of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001332677.1
NM_102349.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within NAD transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within NAD transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
NAD+ transporter 2
NP_564233.1
  • NAD+ transporter 2 (NDT2); FUNCTIONS IN: binding, NAD transporter activity; INVOLVED IN: transport, NAD transport, mitochondrial transport; LOCATED IN: mitochondrial inner membrane, membrane; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial carrier protein (InterPro:IPR002067), Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: NAD+ transporter 1 (TAIR:AT2G47490.1); Has 30606 Blast hits to 14728 proteins in 470 species: Archae - 0; Bacteria - 8; Metazoa - 12581; Fungi - 9084; Plants - 5612; Viruses - 5; Other Eukaryotes - 3316 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    8903405..8906455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102349.4 → NP_564233.1  NAD+ transporter 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564233.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4A3J5, Q8RWA5, Q9C6K8, Q9FRI7
    UniProtKB/TrEMBL
    A0A178WGZ3, A0A5S9VUS6
    Conserved Domains (1) summary
    pfam00153
    Location:213 → 307
    Mito_carr; Mitochondrial carrier protein

  2. NM_001332677.1 → NP_001321077.1  NAD+ transporter 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4A3J5, Q8RWA5, Q9C6K8, Q9FRI7
    UniProtKB/TrEMBL
    A0A178WGZ3, A0A5S9VUS6
    Conserved Domains (1) summary
    pfam00153
    Location:213 → 307
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8RWA5.1

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