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WAK4 wall associated kinase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838716, updated on 18-Sep-2024

Summary

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Official Symbol
WAK4
Official Full Name
wall associated kinase 4
Primary source
TAIR:AT1G21210
Locus tag
AT1G21210
See related
Araport:AT1G21210
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F16F4.10; F16F4_10; wall associated kinase 4
Summary
cell wall-associated ser/thr kinase involved in cell elongation and lateral root development
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Genomic context

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See WAK4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (7423704..7427041)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene sequence-specific DNA binding transcription factor Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene wall associated kinase 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antisense expression of a cell wall-associated protein kinase, WAK4, inhibits cell elongation and alters morphology. Lally D, et al. Plant Cell, 2001 Jun. PMID 11402163, Free PMC Article
  2. A cluster of five cell wall-associated receptor kinase genes, Wak1-5, are expressed in specific organs of Arabidopsis. He ZH, et al. Plant Mol Biol, 1999 Apr. PMID 10380805
  3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables polysaccharide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lateral root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
wall associated kinase 4
NP_173544.1
  • wall associated kinase 4 (WAK4); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding, calcium ion binding; INVOLVED IN: protein amino acid phosphorylation, unidimensional cell growth, lateral root development; LOCATED IN: plasma membrane; EXPRESSED IN: root, trichome; CONTAINS InterPro DOMAIN/s: EGF-like calcium-binding (InterPro:IPR001881), EGF-like, type 3 (InterPro:IPR000742), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EGF-like calcium-binding, conserved site (InterPro:IPR018097), EGF-type aspartate/asparagine hydroxylation site (InterPro:IPR000152), EGF calcium-binding (InterPro:IPR013091), EGF-like (InterPro:IPR006210); BEST Arabidopsis thaliana protein match is: wall-associated kinase 2 (TAIR:AT1G21270.1); Has 129683 Blast hits to 121711 proteins in 4745 species: Archae - 127; Bacteria - 14044; Metazoa - 54379; Fungi - 9626; Plants - 33474; Viruses - 427; Other Eukaryotes - 17606 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    7423704..7427041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101974.3 → NP_173544.1  wall associated kinase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173544.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81819, Q9LMN6
    UniProtKB/TrEMBL
    A0A178W780
    Conserved Domains (3) summary
    cd14066
    Location:416 → 683
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam07645
    Location:279 → 324
    EGF_CA; Calcium-binding EGF domain
    pfam13947
    Location:25 → 125
    GUB_WAK_bind; Wall-associated receptor kinase galacturonan-binding
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LMN6.1

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