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HMGB3 high mobility group B3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838659, updated on 18-Sep-2024

Summary

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Official Symbol
HMGB3
Official Full Name
high mobility group B3
Primary source
TAIR:AT1G20696
Locus tag
AT1G20696
See related
Araport:AT1G20696
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
high mobility group B3; NFD03; NFD3; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR
Summary
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha.
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Genomic context

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See HMGB3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (7179273..7181574)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SWI-SNF-related chromatin binding protein Neighboring gene ncRNA Neighboring gene high mobility group B2 Neighboring gene WUSCHEL related homeobox 14 Neighboring gene WUSCHEL related homeobox 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleocytoplasmic distribution of the Arabidopsis chromatin-associated HMGB2/3 and HMGB4 proteins. Pedersen DS, et al. Plant Physiol, 2010 Dec. PMID 20940346, Free PMC Article
  2. Phosphorylation of maize and Arabidopsis HMGB proteins by protein kinase CK2alpha. Stemmer C, et al. Biochemistry, 2003 Apr 1. PMID 12653554
  3. Variability in Arabidopsis thaliana chromosomal high-mobility-group-1-like proteins. Stemmer C, et al. Eur J Biochem, 1997 Dec 15. PMID 9461286
  4. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
  5. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001035998.1
NM_001084101.2
NM_001332459.1
NM_101921.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables chromatin binding TAS
Traceable Author Statement
more info
 PubMed 
enables structural constituent of chromatin TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chromatin TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
high mobility group B3
NP_001031075.1
  • high mobility group B3 (HMGB3); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910); BEST Arabidopsis thaliana protein match is: high mobility group B2 (TAIR:AT1G20693.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001077570.2
  • high mobility group B3 (HMGB3); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910); BEST Arabidopsis thaliana protein match is: high mobility group B2 (TAIR:AT1G20693.2); Has 5742 Blast hits to 4932 proteins in 507 species: Archae - 0; Bacteria - 0; Metazoa - 4274; Fungi - 383; Plants - 553; Viruses - 0; Other Eukaryotes - 532 (source: NCBI BLink).
NP_564124.1
  • high mobility group B3 (HMGB3); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910); BEST Arabidopsis thaliana protein match is: high mobility group B2 (TAIR:AT1G20693.2); Has 5914 Blast hits to 5088 proteins in 514 species: Archae - 0; Bacteria - 0; Metazoa - 4343; Fungi - 437; Plants - 569; Viruses - 4; Other Eukaryotes - 561 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    7179273..7181574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001332458.1 → NP_001322267.1  high mobility group B3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8ATJ7

  2. NM_101921.4 → NP_564124.1  high mobility group B3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564124.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MQS4, P93047, Q2L6T4
    UniProtKB/TrEMBL
    A0A178W6Y6
    Conserved Domains (1) summary
    pfam00505
    Location:35 → 103
    HMG_box; HMG (high mobility group) box

  3. NM_001332459.1 → NP_001322266.1  high mobility group B3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8ATG5

  4. NM_001035998.1 → NP_001031075.1  high mobility group B3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031075.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9VCC0, A0A654ECM5
    Conserved Domains (1) summary
    cd01390
    Location:35 → 101
    HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...

  5. NM_001084101.2 → NP_001077570.2  high mobility group B3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H1ZEC3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P93047.1

Gene LinkOut

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