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ketose-bisphosphate aldolase class-II family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838407, updated on 18-Sep-2024

Summary

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Official Full Name
ketose-bisphosphate aldolase class-II family protein
Primary source
TAIR:AT1G18270
Locus tag
AT1G18270
See related
Araport:AT1G18270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T10O22.24; T10O22_24
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Genomic context

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Location:
chromosome: 1
Exon count:
42
Sequence:
Chromosome: 1; NC_003070.9 (6283370..6293993, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HCP-like superfamily protein Neighboring gene zein-binding protein (Protein of unknown function, DUF593) Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene DUF4228 domain protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
  2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001123831.1
NM_001198099.1
NM_001332339.1
NM_101685.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables aldehyde-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ketose-bisphosphate aldolase class-II family protein
NP_001117303.1
  • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001185028.1
  • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1).
NP_173263.2
  • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 34046 Blast hits to 22505 proteins in 2700 species: Archae - 264; Bacteria - 21742; Metazoa - 568; Fungi - 820; Plants - 423; Viruses - 1; Other Eukaryotes - 10228 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6283370..6293993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101685.5 → NP_173263.2  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173263.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9UZZ2, A0A654ECE6, Q8VYC5
    Conserved Domains (1) summary
    PLN02858
    Location:1 → 1373
    PLN02858; fructose-bisphosphate aldolase

  2. NM_001332339.1 → NP_001322878.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AVD8, A0A5S9UZZ2

  3. NM_001123831.1 → NP_001117303.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001117303.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9UZZ2, B3H739
    Conserved Domains (7) summary
    PLN02858
    Location:1 → 1374
    PLN02858; fructose-bisphosphate aldolase
    pfam01116
    Location:1098 → 1373
    F_bP_aldolase; Fructose-bisphosphate aldolase class-II
    pfam03446
    Location:324 → 484
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
    pfam07005
    Location:656 → 894
    DUF1537; Putative sugar-binding N-terminal domain
    pfam14833
    Location:489 → 609
    NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
    pfam17042
    Location:918 → 1084
    DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
    cl21454
    Location:5 → 158
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. NM_001198099.1 → NP_001185028.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001185028.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9UZZ2, F4IAP5
    Conserved Domains (7) summary
    PLN02858
    Location:1 → 1393
    PLN02858; fructose-bisphosphate aldolase
    pfam01116
    Location:1117 → 1392
    F_bP_aldolase; Fructose-bisphosphate aldolase class-II
    pfam03446
    Location:323 → 483
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
    pfam07005
    Location:655 → 913
    DUF1537; Putative sugar-binding N-terminal domain
    pfam14833
    Location:488 → 608
    NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
    pfam17042
    Location:937 → 1103
    DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
    cl21454
    Location:5 → 157
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
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