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Disease resistance protein (TIR-NBS class) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838337, updated on 18-Sep-2024

Summary

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Official Full Name
Disease resistance protein (TIR-NBS class)
Primary source
TAIR:AT1G17610
Locus tag
AT1G17610
See related
Araport:AT1G17610
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CHILLING SENSITIVE 1; CHS1; F11A6.20; F11A6_20
Summary
Mutant accumulates steryl-esters at low temperature.
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Genomic context

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Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (6054922..6058357)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene myosin 1 Neighboring gene nuclear factor Y, subunit A8 Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance protein (TIR-NBS class) Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A TIR-NBS protein encoded by Arabidopsis Chilling Sensitive 1 (CHS1) limits chloroplast damage and cell death at low temperature. Zbierzak AM, et al. Plant J, 2013 Aug. PMID 23617639
  2. Permeability of boric acid across lipid bilayers and factors affecting it. Dordas C, et al. J Membr Biol, 2000 May 15. PMID 10811971
  3. Temperature-dependent autoimmunity mediated by chs1 requires its neighboring TNL gene SOC3. Zhang Y, et al. New Phytol, 2017 Feb. PMID 27699788
  4. A missense mutation in CHS1, a TIR-NB protein, induces chilling sensitivity in Arabidopsis. Wang Y, et al. Plant J, 2013 Aug. PMID 23651299
  5. TIR-NB-LRR immune receptor SOC3 pairs with truncated TIR-NB protein CHS1 or TN2 to monitor the homeostasis of E3 ligase SAUL1. Liang W, et al. New Phytol, 2019 Mar. PMID 30317650

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. differential pairings of typical Toll Interleukin1 receptor (TIR) type NLR (TNL) receptor SOC3 with atypical truncated TIR-NB (TN) proteins CHS1 or TN2 to guard the homeostasis of the E3 ligase SAUL1, are reported.
    Title: TIR-NB-LRR immune receptor SOC3 pairs with truncated TIR-NB protein CHS1 or TN2 to monitor the homeostasis of E3 ligase SAUL1.
  2. This study reveals that the TN protein CHS1 interacts with the TNL protein SOC3 to modulate temperature-dependent autoimmunity.
    Title: Temperature-dependent autoimmunity mediated by chs1 requires its neighboring TNL gene SOC3.
  3. A map-based cloning analysis revealed that CHS1 encodes a TIR-NB-type protein. The chilling sensitivity of chs1 was fully rescued by pad4 and eds1, but not by ndr1.
    Title: A missense mutation in CHS1, a TIR-NB protein, induces chilling sensitivity in Arabidopsis.
  4. CHS1 acts at an intersection between temperature sensing and biotic stress pathway activation to maintain plant performance over a range of conditions.
    Title: A TIR-NBS protein encoded by Arabidopsis Chilling Sensitive 1 (CHS1) limits chloroplast damage and cell death at low temperature.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_001332314.1
NM_101623.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables NAD+ nucleotidase, cyclic ADP-ribose generating IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within borate transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to cold IMP
Inferred from Mutant Phenotype
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Disease resistance protein (TIR-NBS class)
NP_001319029.1
  • Disease resistance protein (TIR-NBS class); FUNCTIONS IN: transmembrane receptor activity, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS class) (TAIR:AT5G40090.1); Has 6872 Blast hits to 6811 proteins in 238 species: Archae - 0; Bacteria - 42; Metazoa - 2; Fungi - 5; Plants - 6813; Viruses - 0; Other Eukaryotes - 10 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6054922..6058357
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001332314.1 → NP_001319029.1  Disease resistance protein (TIR-NBS class) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I902, Q9LNP4
    UniProtKB/TrEMBL
    A0A178W479, A0A5S9UW06
    Conserved Domains (1) summary
    PLN03210
    Location:15 → 397
    PLN03210; Resistant to P. syringae 6; Provisional

  2. NM_101623.4 → NP_173204.1  Disease resistance protein (TIR-NBS class) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173204.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I902, Q9LNP4
    UniProtKB/TrEMBL
    A0A178W479, A0A5S9UW06
    Conserved Domains (1) summary
    PLN03210
    Location:15 → 397
    PLN03210; Resistant to P. syringae 6; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4I902.1

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