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EBS3 Alg9-like mannosyltransferase family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838261, updated on 18-Sep-2024

Summary

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Official Symbol
EBS3
Official Full Name
Alg9-like mannosyltransferase family
Primary source
TAIR:AT1G16900
Locus tag
AT1G16900
See related
Araport:AT1G16900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EMS-mutagenized bri1 suppressor 3; F17F16.20
Summary
Encodes the Arabidopsis ortholog of the yeast/human ALG9 catalyzing the luminal addition of two alpha-1,2 Man residues in assembling Glc3Man9GlcNAc2.
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Genomic context

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See EBS3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Sequence:
Chromosome: 1; NC_003070.9 (5779008..5782433, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uridylyltransferase-like protein Neighboring gene ubiquitin-conjugating enzyme 36 Neighboring gene ncRNA Neighboring gene Curculin-like (mannose-binding) lectin family protein Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations of an alpha1,6 mannosyltransferase inhibit endoplasmic reticulum-associated degradation of defective brassinosteroid receptors in Arabidopsis. Hong Z, et al. Plant Cell, 2009 Dec. PMID 20023196, Free PMC Article
  2. Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis. Hong Z, et al. Proc Natl Acad Sci U S A, 2012 Jul 10. PMID 22733738, Free PMC Article
  3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
  4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_101551.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables alpha-1,2-mannosyltransferase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ERAD pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in dolichol-linked oligosaccharide biosynthetic process NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 

General protein information

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Preferred Names
Alg9-like mannosyltransferase family
NP_173134.2
  • Alg9-like mannosyltransferase family; FUNCTIONS IN: sugar binding, transferase activity, transferring glycosyl groups; INVOLVED IN: GPI anchor biosynthetic process; LOCATED IN: intrinsic to endoplasmic reticulum membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Alg9-like mannosyltransferase (InterPro:IPR005599); BEST Arabidopsis thaliana protein match is: Alg9-like mannosyltransferase family (TAIR:AT5G14850.2); Has 817 Blast hits to 803 proteins in 193 species: Archae - 0; Bacteria - 22; Metazoa - 302; Fungi - 301; Plants - 91; Viruses - 0; Other Eukaryotes - 101 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    5779008..5782433 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101551.4 → NP_173134.2  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173134.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FZ49
    UniProtKB/TrEMBL
    A0A178W2J0, A0A654EAJ3, W8QPA0
    Conserved Domains (1) summary
    pfam03901
    Location:48 → 451
    Glyco_transf_22; Alg9-like mannosyltransferase family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FZ49.1

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