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NRB4 mediator of RNA polymerase II transcription subunit 15a-like protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838147, updated on 18-Sep-2024

Summary

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Official Symbol
NRB4
Official Full Name
mediator of RNA polymerase II transcription subunit 15a-like protein
Primary source
TAIR:AT1G15780
Locus tag
AT1G15780
See related
Araport:AT1G15780
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F7H2.12; F7H2_12; Non-Recognition-of-BTH 4
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Genomic context

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See NRB4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Sequence:
Chromosome: 1; NC_003070.9 (5430040..5436618, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene mediator of RNA polymerase II transcription subunit Neighboring gene mediator of RNA polymerase II transcription subunit Neighboring gene mediator of RNA polymerase II transcription subunit 15a-like protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Non-recognition-of-BTH4, an Arabidopsis mediator subunit homolog, is necessary for development and response to salicylic acid. Canet JV, et al. Plant Cell, 2012 Oct. PMID 23064321, Free PMC Article
  2. KIX domain of AtMed15a, a Mediator subunit of Arabidopsis, is required for its interaction with different proteins. Kumar V, et al. Plant Signal Behav, 2018 Feb 1. PMID 29341856, Free PMC Article
  3. The Mediator Complex MED15 Subunit Mediates Activation of Downstream Lipid-Related Genes by the WRINKLED1 Transcription Factor. Kim MJ, et al. Plant Physiol, 2016 Jul. PMID 27246098, Free PMC Article
  4. Purification of a plant mediator from Arabidopsis thaliana identifies PFT1 as the Med25 subunit. Bäckström S, et al. Mol Cell, 2007 Jun 8. PMID 17560376
  5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. At1g15780 is part of Mediator complex and transcriptionally regulates glycolysis-related and fatty acid biosynthetic genes during embryogenesis.MED15 was recruited to the promoters of WRI1 target genes.
    Title: The Mediator Complex MED15 Subunit Mediates Activation of Downstream Lipid-Related Genes by the WRINKLED1 Transcription Factor.
  2. NRB4 (At1g15780) functions downstream of NPR1 to regulate the SA response.
    Title: Non-recognition-of-BTH4, an Arabidopsis mediator subunit homolog, is necessary for development and response to salicylic acid.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001332183.1
NM_001332184.1
NM_101446.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables chromatin DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of fatty acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to salicylic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
part_of mediator complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
mediator of RNA polymerase II transcription subunit 15a-like protein
NP_173030.1
  • unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G10440.1); Has 103701 Blast hits to 43153 proteins in 1828 species: Archae - 30; Bacteria - 7385; Metazoa - 38639; Fungi - 11531; Plants - 7727; Viruses - 307; Other Eukaryotes - 38082 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    5430040..5436618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101446.4 → NP_173030.1  mediator of RNA polymerase II transcription subunit 15a-like protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173030.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I171, Q56WT7, Q9LMQ6
    UniProtKB/TrEMBL
    A0A654EA43
    Conserved Domains (1) summary
    pfam16987
    Location:25 → 100
    KIX_2; KIX domain

  2. NM_001332183.1 → NP_001321151.1  mediator of RNA polymerase II transcription subunit 15a-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AQ17, A0A654EA43

  3. NM_001332184.1 → NP_001321150.1  mediator of RNA polymerase II transcription subunit 15a-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AQ03, A0A654EA43
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4I171.1

Gene LinkOut

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