U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

semialdehyde dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838046, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Full Name
semialdehyde dehydrogenase family protein
Primary source
TAIR:AT1G14810
Locus tag
AT1G14810
See related
Araport:AT1G14810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F10B6.22; F10B6_22
Summary
encodes an aspartate semialdehyde dehydrogenase, which produces the branch point intermediate for lysine and threonine/methionine biosynthesis
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (5102424..5104850, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene MAC/Perforin domain-containing protein Neighboring gene RNA-dependent RNA polymerase 1 Neighboring gene Nucleic acid-binding, OB-fold-like protein Neighboring gene ncRNA Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene DYNAMIN-like 1C Neighboring gene microtubule-associated proteins 70-4

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Overproduction, purification, and characterization of recombinant aspartate semialdehyde dehydrogenase from Arabidopsis thaliana. Paris S, et al. Protein Expr Purif, 2002 Feb. PMID 11812229
  2. Tip Growth Defective1 interacts with the cellulose synthase complex to regulate cellulose synthesis in Arabidopsis thaliana. Lampugnani ER, et al. PLoS One, 2024. PMID 38358988, Free PMC Article
  3. The Extra-Pathway Interactome of the TCA Cycle: Expected and Unexpected Metabolic Interactions. Zhang Y, et al. Plant Physiol, 2018 Jul. PMID 29794018, Free PMC Article
  4. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
  5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001332137.1
NM_101350.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables aspartate-semialdehyde dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in isoleucine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lysine biosynthetic process via diaminopimelate IEA
Inferred from Electronic Annotation
more info
  
involved_in threonine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in plastid HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
semialdehyde dehydrogenase family protein
NP_172934.1
  • semialdehyde dehydrogenase family protein; FUNCTIONS IN: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, aspartate-semialdehyde dehydrogenase activity; INVOLVED IN: cellular amino acid biosynthetic process, oxidation reduction, threonine biosynthetic process, methionine biosynthetic process, cellular amino acid metabolic process; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Semialdehyde dehydrogenase, dimerisation domain (InterPro:IPR012280), Semialdehyde dehydrogenase, NAD-binding (InterPro:IPR000534), Aspartate-semialdehyde dehydrogenase, bacterial (InterPro:IPR005986), Aspartate-semialdehyde dehydrogenase (InterPro:IPR012080); Has 10268 Blast hits to 10266 proteins in 2514 species: Archae - 260; Bacteria - 6386; Metazoa - 3; Fungi - 175; Plants - 61; Viruses - 0; Other Eukaryotes - 3383 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    5102424..5104850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101350.4 → NP_172934.1  semialdehyde dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172934.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W3P2, Q8VYI4, Q9FVC4
    Conserved Domains (1) summary
    PLN02383
    Location:32 → 375
    PLN02383; aspartate semialdehyde dehydrogenase

  2. NM_001332137.1 → NP_001320803.1  semialdehyde dehydrogenase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8ANY1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools