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PP2AA3 protein phosphatase 2A subunit A3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837892, updated on 18-Sep-2024

Summary

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Official Symbol
PP2AA3
Official Full Name
protein phosphatase 2A subunit A3
Primary source
TAIR:AT1G13320
Locus tag
AT1G13320
See related
Araport:AT1G13320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
65 KDA REGULATORY SUBUNIT OF PROTEIN PHOSPHATASE 2A; PR65; protein phosphatase 2A subunit A3; protein phosphatase 2A subunit A3; T6J4.8; T6J4_8
Summary
one of three genes encoding the 65 kDa regulatory subunit of protein phosphatase 2A (PP2A)
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Genomic context

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See PP2AA3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Sequence:
Chromosome: 1; NC_003070.9 (4563428..4567849, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene myb-like transcription factor family protein Neighboring gene Endosomal targeting BRO1-like domain-containing protein Neighboring gene Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) Neighboring gene Regulator of Vps4 activity in the MVB pathway protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterisation of cDNA and genomic clones encoding homologues of the 65 kDa regulatory subunit of protein phosphatase 2A in Arabidopsis thaliana. Slabas AR, et al. Plant Mol Biol, 1994 Nov. PMID 7811971
  2. The Arabidopsis TONNEAU2 gene encodes a putative novel protein phosphatase 2A regulatory subunit essential for the control of the cortical cytoskeleton. Camilleri C, et al. Plant Cell, 2002 Apr. PMID 11971138, Free PMC Article
  3. Arabidopsis thaliana histone deacetylase 14 (HDA14) is an α-tubulin deacetylase that associates with PP2A and enriches in the microtubule fraction with the putative histone acetyltransferase ELP3. Tran HT, et al. Plant J, 2012 Jul. PMID 22404109
  4. TIME FOR COFFEE represses accumulation of the MYC2 transcription factor to provide time-of-day regulation of jasmonate signaling in Arabidopsis. Shin J, et al. Plant Cell, 2012 Jun. PMID 22693280, Free PMC Article
  5. A PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Dai M, et al. Plant Cell, 2012 Jun. PMID 22715043, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001035958.1
NM_001198052.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plant-type cell wall HDA PubMed 
located_in plasma membrane HDA PubMed 
part_of protein phosphatase type 2A complex TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase 2A subunit A3
NP_001031035.1
  • protein phosphatase 2A subunit A3 (PP2AA3); FUNCTIONS IN: binding, protein phosphatase type 2A regulator activity; INVOLVED IN: regulation of phosphorylation; LOCATED IN: cell wall, plasma membrane, protein phosphatase type 2A complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A subunit A2 (TAIR:AT3G25800.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001184981.1
  • protein phosphatase 2A subunit A3 (PP2AA3); FUNCTIONS IN: binding, protein phosphatase type 2A regulator activity; INVOLVED IN: regulation of phosphorylation; LOCATED IN: protein phosphatase type 2A complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A subunit A2 (TAIR:AT3G25800.1).
NP_172790.2
  • protein phosphatase 2A subunit A3 (PP2AA3); FUNCTIONS IN: binding, protein phosphatase type 2A regulator activity; INVOLVED IN: regulation of phosphorylation; LOCATED IN: cell wall, plasma membrane, protein phosphatase type 2A complex; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A subunit A2 (TAIR:AT3G25800.1); Has 2761 Blast hits to 1677 proteins in 248 species: Archae - 13; Bacteria - 63; Metazoa - 1436; Fungi - 398; Plants - 296; Viruses - 0; Other Eukaryotes - 555 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    4563428..4567849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101203.5 → NP_172790.2  protein phosphatase 2A subunit A3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172790.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38951, Q8LPH9, Q9FX65
    Conserved Domains (4) summary
    COG1413
    Location:193 → 419
    HEAT; HEAT repeat [General function prediction only]
    pfam12755
    Location:220 → 300
    Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
    pfam13646
    Location:356 → 461
    HEAT_2; HEAT repeats
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]

  2. NM_001332065.1 → NP_001320387.1  protein phosphatase 2A subunit A3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AMM6

  3. NM_001198052.1 → NP_001184981.1  protein phosphatase 2A subunit A3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184981.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38951, Q8LPH9, Q9FX65
    Conserved Domains (4) summary
    COG1413
    Location:193 → 419
    HEAT; HEAT repeat [General function prediction only]
    pfam12755
    Location:220 → 300
    Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
    pfam13646
    Location:356 → 461
    HEAT_2; HEAT repeats
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]

  4. NM_001035958.1 → NP_001031035.1  protein phosphatase 2A subunit A3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031035.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4HQR5
    Conserved Domains (4) summary
    COG1413
    Location:193 → 419
    HEAT; HEAT repeat [General function prediction only]
    pfam12755
    Location:220 → 300
    Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
    pfam13646
    Location:356 → 461
    HEAT_2; HEAT repeats
    sd00044
    Location:243 → 267
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38951.2

Gene LinkOut

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