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ERF1-2 eukaryotic release factor 1-2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837850, updated on 18-Sep-2024

Summary

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Official Symbol
ERF1-2
Official Full Name
eukaryotic release factor 1-2
Primary source
TAIR:AT1G12920
Locus tag
AT1G12920
See related
Araport:AT1G12920
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
eukaryotic release factor 1-2; F13K23.17; F13K23_17
Summary
Encodes a eukaryotic release factor one homolog.
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Genomic context

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See ERF1-2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
2
Sequence:
Chromosome: 1; NC_003070.9 (4396348..4398193, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glyceraldehyde 3-phosphate dehydrogenase A subunit 2 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene ARM repeat superfamily protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling development. Zhou X, et al. J Exp Bot, 2010. PMID 19939886, Free PMC Article
  2. Translation termination in Arabidopsis thaliana: characterisation of three versions of release factor 1. Chapman B, et al. Gene, 2004 Oct 27. PMID 15474304
  3. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
  4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
  5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. eRF1-2 affects glucose and phytohormone responses in modulating plant growth and development.
    Title: Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_101163.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables translation release factor activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within translational termination IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 
part_of translation release factor complex TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
eukaryotic release factor 1-2
NP_172752.1
  • eukaryotic release factor 1-2 (ERF1-2); FUNCTIONS IN: translation release factor activity; INVOLVED IN: translational termination; LOCATED IN: translation release factor complex, plasma membrane; EXPRESSED IN: leaf; CONTAINS InterPro DOMAIN/s: eRF1 domain 2 (InterPro:IPR005141), eRF1 domain 3 (InterPro:IPR005142), eRF1 domain 1 (InterPro:IPR005140), Peptide chain release factor eRF1/aRF1 (InterPro:IPR004403); BEST Arabidopsis thaliana protein match is: eukaryotic release factor 1-3 (TAIR:AT3G26618.1); Has 1141 Blast hits to 1136 proteins in 380 species: Archae - 310; Bacteria - 0; Metazoa - 243; Fungi - 154; Plants - 143; Viruses - 3; Other Eukaryotes - 288 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    4396348..4398193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101163.2 → NP_172752.1  eukaryotic release factor 1-2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172752.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q147G8, Q39098, Q39223, Q41987, Q9LPV8
    UniProtKB/TrEMBL
    A0A178W3T8, A0A5S9U337, A0A5S9XFZ2
    Conserved Domains (1) summary
    COG1503
    Location:1 → 418
    eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LPV8.1

Gene LinkOut

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