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OTS2 Cysteine proteinases superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837598, updated on 18-Sep-2024

Summary

Official Symbol
OTS2
Official Full Name
Cysteine proteinases superfamily protein
Primary source
TAIR:AT1G10570
Locus tag
AT1G10570
See related
Araport:AT1G10570
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
OVERLY TOLERANT TO SALT 2; T10O24.20; T10O24_20; UB-LIKE PROTEASE 1C; ULP1C
Summary
Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave the C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. sYFP:OTS2 protein accumulates in nuclei in a punctate pattern. Double mutant analysis with ULP1D/OTS1 indicates that these genes are involved in salt stress responses and flowering time regulation.
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Genomic context

See OTS2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Sequence:
Chromosome: 1; NC_003070.9 (3487386..3491277)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene xyloglucan:xyloglucosyl transferase 33 Neighboring gene plant U-box 18 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

NM_001331913.1
NM_100932.4
NM_202073.4

Gene Ontology Provided by TAIR

Component Evidence Code Pubs
located_in nucleus PubMed 
located_in nucleus  

General protein information

Preferred Names
Cysteine proteinases superfamily protein
NP_172527.2
  • OVERLY TOLERANT TO SALT 2 (OTS2); CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); BEST Arabidopsis thaliana protein match is: UB-like protease 1D (TAIR:AT1G60220.1); Has 1265 Blast hits to 1250 proteins in 204 species: Archae - 0; Bacteria - 0; Metazoa - 616; Fungi - 251; Plants - 239; Viruses - 3; Other Eukaryotes - 156 (source: NCBI BLink).
NP_973802.1
  • OVERLY TOLERANT TO SALT 2 (OTS2); CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); BEST Arabidopsis thaliana protein match is: UB-like protease 1D (TAIR:AT1G60220.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3487386..3491277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_202073.4 → NP_973802.1  Cysteine proteinases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_973802.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W2X8, A0A5S9TNT4, A0A654EJB6
    Conserved Domains (1) summary
    pfam02902
    Location:344 → 545
    Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
  2. NM_001331913.1 → NP_001322371.1  Cysteine proteinases superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W346, A0A1P8ATS5, A0A384LH87
  3. NM_100932.4 → NP_172527.2  Cysteine proteinases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172527.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3EDF1, Q8RWN0, Q9XIJ4
    UniProtKB/TrEMBL
    A0A5S9TNT4, A0A654EJB6
    Conserved Domains (1) summary
    pfam02902
    Location:345 → 545
    Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain
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