U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BCAT-1 branched-chain amino acid transaminase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837542, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
BCAT-1
Official Full Name
branched-chain amino acid transaminase 1
Primary source
TAIR:AT1G10060
Locus tag
AT1G10060
See related
Araport:AT1G10060
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATBCAT-1; BCAT1; branched-chain amino acid transaminase 1; branched-chain amino acid transferase 1; T27I1.8; T27I1_8
Summary
encodes a mitochondrial branched-chain amino acid aminotransferase. Complements the yeast leu/iso-leu/val auxotrophy mutant.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See BCAT-1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Sequence:
Chromosome: 1; NC_003070.9 (3284073..3287292)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ergosterol biosynthesis protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein Neighboring gene branched-chain amino acid transaminase 2 Neighboring gene Early-responsive to dehydration stress protein (ERD4) Neighboring gene Protein prenylyltransferase superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana. Schuster J, et al. Plant Mol Biol, 2005 Jan. PMID 15821880
  2. Genome-wide analysis of branched-chain amino acid levels in Arabidopsis seeds. Angelovici R, et al. Plant Cell, 2013 Dec. PMID 24368787, Free PMC Article
  3. The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins. Diebold R, et al. Plant Physiol, 2002 Jun. PMID 12068099, Free PMC Article
  4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BCAT2, and not BCAT1, is the causal gene driving seed branched-chain amino acid natural variation.
    Title: Genome-wide analysis of branched-chain amino acid levels in Arabidopsis seeds.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_001123785.1
NM_001331883.1
NM_100880.3
NM_179298.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables L-isoleucine-2-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables L-leucine-2-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables L-valine-2-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables branched-chain-amino-acid transaminase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain-amino-acid transaminase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in valine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
branched-chain amino acid transaminase 1
NP_001117257.1
  • branched-chain amino acid transaminase 1 (BCAT-1); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, protein binding, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid transaminase 2 (TAIR:AT1G10070.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_563859.1
  • branched-chain amino acid transaminase 1 (BCAT-1); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, protein binding, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid transaminase 2 (TAIR:AT1G10070.2); Has 6519 Blast hits to 6519 proteins in 2279 species: Archae - 103; Bacteria - 4487; Metazoa - 263; Fungi - 384; Plants - 208; Viruses - 0; Other Eukaryotes - 1074 (source: NCBI BLink).
NP_849629.1
  • branched-chain amino acid transaminase 1 (BCAT-1); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, protein binding, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid transaminase 2 (TAIR:AT1G10070.2); Has 12211 Blast hits to 12211 proteins in 2505 species: Archae - 154; Bacteria - 7688; Metazoa - 265; Fungi - 412; Plants - 248; Viruses - 0; Other Eukaryotes - 3444 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3284073..3287292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001331880.1 → NP_001320930.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8APA3

  2. NM_001331881.1 → NP_001320929.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WHD8, A0A1P8APA5

  3. NM_001331882.1 → NP_001320928.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8APB7

  4. NM_179298.2 → NP_849629.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849629.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O80597, Q93Y32
    UniProtKB/TrEMBL
    A0A178WHD8, B9DFH1
    Conserved Domains (2) summary
    PLN02883
    Location:1 → 384
    PLN02883; Branched-chain amino acid aminotransferase
    cd01557
    Location:90 → 371
    BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...

  5. NM_100880.3 → NP_563859.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_563859.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I2Q0
    Conserved Domains (1) summary
    cl00224
    Location:90 → 296
    PLPDE_IV; PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate ...

  6. NM_001331883.1 → NP_001320927.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WHD8, A0A1P8APE4

  7. NM_001123785.1 → NP_001117257.1  branched-chain amino acid transaminase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001117257.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654EAD5, B3H7M6
    Conserved Domains (1) summary
    cd01557
    Location:24 → 305
    BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93Y32.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.