MYB60 myb domain protein 60 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MYB60
Official Full Name: myb domain protein 60
Primary source: TAIR:AT1G08810
Locus tag: AT1G08810
See related: Araport:AT1G08810
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtMYB60; F22O13.30; F22O13_30; myb domain protein 60
Summary: putative transcription factor of the R2R3-MYB gene family. Transcript increases under conditions that promote stomatal opening (white and blue light, abi1-1 mutation) and decreases under conditions that trigger stomatal closure (ABA, desiccation, darkness), with the exception of elevated CO2. Expressed exclusively in guard cells of all tissues. It is required for light-induced opening of stomata. Mutant shows reduced stomatal aperture which helps to limit water loss during drought.
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Genomic context

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See MYB60 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Sequence:: Chromosome: 1; NC_003070.9 (2819065..2820478, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The AtMYB60 transcription factor regulates stomatal opening by modulating oxylipin synthesis in guard cells.
Title: The AtMYB60 transcription factor regulates stomatal opening by modulating oxylipin synthesis in guard cells.
DOF-binding sites are required for AtMYB60 guard-cells expression.
Title: DOF-binding sites additively contribute to guard cell-specificity of AtMYB60 promoter.
MYB60 plays a dual role in abiotic stress responses in Arabidopsis through its involvement in stomatal regulation and root growth.
Title: A dual role for MYB60 in stomatal regulation and root growth of Arabidopsis thaliana under drought stress.
Results demonstrate that phyB and CRY might regulate stomatal opening, at least in part, by regulating MYB60 expression.
Title: Phytochrome B is involved in mediating red light-induced stomatal opening in Arabidopsis thaliana.
Overexpression of transcription factor AtMYB60 represses anthocyanin biosynthesis in lettuce.
Title: Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa).
AtMYB60 regulates stomatal movements and plant drought tolerance as a transcriptional modulator of physiological responses in guard cells.
Title: A guard-cell-specific MYB transcription factor regulates stomatal movements and plant drought tolerance.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001331790.1

Supported by ESTs:

NM_100755.3

Supported by ESTs:

NM_202066.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	TAS Traceable Author Statement more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to UV	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to absence of light	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to auxin	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to blue light	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to cold	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to salt	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to sucrose	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within stomatal movement	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: myb domain protein 60

NP_001318958.1

myb domain protein 60 (MYB60); CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 96 (TAIR:AT5G62470.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_172358.1

myb domain protein 60 (MYB60); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 96 (TAIR:AT5G62470.2); Has 8826 Blast hits to 8217 proteins in 521 species: Archae - 0; Bacteria - 0; Metazoa - 784; Fungi - 468; Plants - 5803; Viruses - 7; Other Eukaryotes - 1764 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

2819065..2820478 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_100755.3 → NP_172358.1 myb domain protein 60 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172358.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D2CFP9, Q3E6Y6, Q8GYP5, Q9FRQ8, Q9SBG0

UniProtKB/TrEMBL

A0A178WD25, A0A5S9TCK3

Conserved Domains (1) summary

PLN03212
Location:5 → 125

PLN03212; Transcription repressor MYB5; Provisional
NM_001331790.1 → NP_001318958.1 myb domain protein 60 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

Q3E6Y6

Conserved Domains (1) summary

PLN03212
Location:5 → 42

PLN03212; Transcription repressor MYB5; Provisional
NM_202066.1 → NP_973795.1 myb domain protein 60 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973795.1

Status: REVIEWED

UniProtKB/TrEMBL

Q3E6Y6

Conserved Domains (1) summary

PLN03212
Location:5 → 42

PLN03212; Transcription repressor MYB5; Provisional