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ATRX P-loop containing nucleoside triphosphate hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837382, updated on 18-Sep-2024

Summary

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Official Symbol
ATRX
Official Full Name
P-loop containing nucleoside triphosphate hydrolases superfamily protein
Primary source
TAIR:AT1G08600
Locus tag
AT1G08600
See related
Araport:AT1G08600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CHR20; F22O13.8; F22O13_8
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Genomic context

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See ATRX in Genome Data Viewer
Location:
chromosome: 1
Exon count:
28
Sequence:
Chromosome: 1; NC_003070.9 (2723677..2733613)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene ncRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene Transcription factor jumonji (jmj) family protein / zinc finger (C5HC2 type) family protein Neighboring gene threonine aldolase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ATRX is involved in H3.3 deposition and in adjusting genome expression.
    Title: Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001198009.1
NM_001198010.1
NM_100733.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
  
enables histone binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables histone chaperone activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within maintenance of rDNA IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
P-loop containing nucleoside triphosphate hydrolases superfamily protein
NP_001184937.1
  • ATRX; FUNCTIONS IN: helicase activity, DNA binding, nucleic acid binding, ATP binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: homolog of RAD54 (TAIR:AT3G19210.1).
NP_001184938.1
  • ATRX; FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: homolog of RAD54 (TAIR:AT3G19210.1).
NP_001184939.1
  • ATRX; FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: homolog of RAD54 (TAIR:AT3G19210.1).
NP_172336.4
  • ATRX; FUNCTIONS IN: helicase activity, DNA binding, nucleic acid binding, ATP binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: homolog of RAD54 (TAIR:AT3G19210.1); Has 31658 Blast hits to 23484 proteins in 2032 species: Archae - 346; Bacteria - 7271; Metazoa - 9089; Fungi - 4970; Plants - 2206; Viruses - 434; Other Eukaryotes - 7342 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2723677..2733613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001198008.2 → NP_001184937.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184937.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4HW51, F4HW52, O04048, Q9FRS5
    UniProtKB/TrEMBL
    A0A178VZQ9, A0A654ED47
    Conserved Domains (4) summary
    PRK02224
    Location:1 → 195
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG0553
    Location:647 → 1278
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd11726
    Location:481 → 575
    ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
    cd18069
    Location:719 → 959
    DEXHc_ARIP4; DEXH-box helicase domain of ARIP4

  2. NM_100733.5 → NP_172336.4  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172336.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654ED47
    Conserved Domains (4) summary
    cd00046
    Location:749 → 885
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd11726
    Location:481 → 575
    ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
    pfam00176
    Location:722 → 1020
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1093 → 1221
    Helicase_C; Helicase conserved C-terminal domain

  3. NM_001198009.1 → NP_001184938.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184938.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4HW51, F4HW52, O04048, Q9FRS5
    UniProtKB/TrEMBL
    A0A178VZQ9, A0A654ED47
    Conserved Domains (4) summary
    PRK02224
    Location:1 → 195
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG0553
    Location:647 → 1278
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd11726
    Location:481 → 575
    ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
    cd18069
    Location:719 → 959
    DEXHc_ARIP4; DEXH-box helicase domain of ARIP4

  4. NM_001198010.1 → NP_001184939.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184939.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4HW51, F4HW52, O04048, Q9FRS5
    UniProtKB/TrEMBL
    A0A178VZQ9, A0A654ED47
    Conserved Domains (4) summary
    PRK02224
    Location:1 → 195
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG0553
    Location:647 → 1278
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd11726
    Location:481 → 575
    ADDz_ATRX; ADDz domain found in ATRX (alpha-thalassemia/mental retardation, X-linked)
    cd18069
    Location:719 → 959
    DEXHc_ARIP4; DEXH-box helicase domain of ARIP4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4HW51.2

Gene LinkOut

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