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PDE247 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837083, updated on 18-Sep-2024

Summary

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Official Symbol
PDE247
Official Full Name
Tetratricopeptide repeat (TPR)-like superfamily protein
Primary source
TAIR:AT1G05750
Locus tag
AT1G05750
See related
Araport:AT1G05750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CLB19; pigment defective 247; T20M3.1; T20M3_1
Summary
Encodes a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts.
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Genomic context

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See PDE247 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_003070.9 (1721509..1724734)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene FAM136A-like protein (DUF842) Neighboring gene ncRNA Neighboring gene FAM136A-like protein (DUF842) Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Vacuolar ATPase assembly integral membrane protein VMA21-like domain-containing protein Neighboring gene microRNA ath-MIR5656 precursor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CLB19, a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts. Chateigner-Boutin AL, et al. Plant J, 2008 Nov. PMID 18657233
  2. Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis. Kindgren P, et al. Plant Cell, 2015 Feb. PMID 25649437, Free PMC Article
  3. Two interacting PPR proteins are major Arabidopsis editing factors in plastid and mitochondria. Guillaumot D, et al. Proc Natl Acad Sci U S A, 2017 Aug 15. PMID 28760958, Free PMC Article
  4. Functional analysis of the Arabidopsis thaliana CHLOROPLAST BIOGENESIS 19 pentatricopeptide repeat editing protein. Ramos-Vega M, et al. New Phytol, 2015 Oct. PMID 25980341
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. these analyses provide important clues about the particularities of the CLB19 editing protein.
    Title: Functional analysis of the Arabidopsis thaliana CHLOROPLAST BIOGENESIS 19 pentatricopeptide repeat editing protein.
  2. By altering S motifs in CLB19 and another editing factor, OTP82,the specificity of these factors in vivo, can be altered.
    Title: Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis.
  3. CLB19 (PDE247) is essential for chloroplast development, and is required for the correct RNA editing of the chloroplast clpP and rpoA transcripts.
    Title: CLB19, a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001331574.1
NM_100455.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA modification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Tetratricopeptide repeat (TPR)-like superfamily protein
NP_172066.3
  • pigment defective 247 (PDE247); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: mitochondrial editing factor 21 (TAIR:AT2G20540.1); Has 41993 Blast hits to 13871 proteins in 254 species: Archae - 1; Bacteria - 18; Metazoa - 75; Fungi - 77; Plants - 41230; Viruses - 0; Other Eukaryotes - 592 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1721509..1724734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100455.3 → NP_172066.3  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172066.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9MA50
    UniProtKB/TrEMBL
    A0A178W105
    Conserved Domains (2) summary
    PLN03077
    Location:37 → 488
    PLN03077; Protein ECB2; Provisional
    sd00004
    Location:274 → 301
    PPR; PPR repeat [structural motif]

  2. NM_001331574.1 → NP_001322717.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9MA50
    UniProtKB/TrEMBL
    A0A178W105
    Conserved Domains (2) summary
    PLN03077
    Location:37 → 488
    PLN03077; Protein ECB2; Provisional
    sd00004
    Location:274 → 301
    PPR; PPR repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9MA50.1

Gene LinkOut

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