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RA-5 RAS 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837023, updated on 18-Sep-2024

Summary

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Official Symbol
RA-5
Official Full Name
RAS 5
Primary source
TAIR:AT1G02130
Locus tag
AT1G02130
See related
Araport:AT1G02130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARA-5; ARA5; ARABIDOPSIS RAS 5; ARABIDOPSIS THALIANA RAB D2A; ARABIDOPSIS THALIANA RESPONSIVE TO ABSCISIC ACID 1B; ATRAB1B; ATRABD2A; RAB D2A; RABD2A; RAS 5; T7I23.6; T7I23_6
Summary
Belongs to the Rab1 GTPase subfamily. This small GTP-binding protein is required in ER to Golgi transportation.
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Genomic context

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See RA-5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (399983..401919, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Leucine carboxyl methyltransferase Neighboring gene bZIP domain class transcription factor (DUF630 and DUF632) Neighboring gene GRAM domain family protein Neighboring gene ncRNA Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A rab1 GTPase is required for transport between the endoplasmic reticulum and golgi apparatus and for normal golgi movement in plants. Batoko H, et al. Plant Cell, 2000 Nov. PMID 11090219, Free PMC Article
  2. Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway. Pinheiro H, et al. J Cell Sci, 2009 Oct 15. PMID 19789181, Free PMC Article
  3. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
  4. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Rab-D1 and Rab-D2 subclasses have overlapping functions in the early secretory pathway. [Rab-D2a]
    Title: Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_100093.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in trans-Golgi network membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
RAS 5
NP_171715.1
  • RAS 5 (RA-5); FUNCTIONS IN: GTP binding; INVOLVED IN: response to cadmium ion, ER to Golgi vesicle-mediated transport; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog 1A (TAIR:AT5G47200.1); Has 30420 Blast hits to 30350 proteins in 816 species: Archae - 27; Bacteria - 199; Metazoa - 15882; Fungi - 4318; Plants - 3658; Viruses - 20; Other Eukaryotes - 6316 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    399983..401919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100093.4 → NP_171715.1  RAS 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_171715.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28188, Q940Z7
    UniProtKB/TrEMBL
    A0A178WIV4, A0A5S9S533
    Conserved Domains (1) summary
    cd01869
    Location:7 → 172
    Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28188.3

Gene LinkOut

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