U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

lactate/malate dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835945, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Full Name
lactate/malate dehydrogenase family protein
Primary source
TAIR:AT5G58330
Locus tag
AT5G58330
See related
Araport:AT5G58330
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MCK7.20; MCK7_20; NADP-dependent Malate Dehydrogenase; NADP-MDH
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
12
Sequence:
Chromosome: 5; NC_003076.8 (23579722..23582395, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene methyl esterase 18 Neighboring gene ncRNA Neighboring gene Kinase interacting (KIP1-like) family protein Neighboring gene myb-like HTH transcriptional regulator family protein Neighboring gene with no lysine (K) kinase 4 Neighboring gene ovate family protein 3

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. High light response of the thylakoid proteome in arabidopsis wild type and the ascorbate-deficient mutant vtc2-2. A comparative proteomics study. Giacomelli L, et al. Plant Physiol, 2006 Jun. PMID 16648217, Free PMC Article
  2. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804
  3. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
  4. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
  5. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_125218.4
NM_180883.3
NM_203229.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables L-malate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables L-malate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to redox state IMP
Inferred from Mutant Phenotype
more info
  
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion HDA PubMed 
located_in plastid HDA PubMed 
located_in thylakoid HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
lactate/malate dehydrogenase family protein
NP_568875.2
  • lactate/malate dehydrogenase family protein; FUNCTIONS IN: oxidoreductase activity, malate dehydrogenase activity, binding, catalytic activity, malate dehydrogenase (NADP+) activity; INVOLVED IN: oxidation reduction, malate metabolic process, carbohydrate metabolic process, metabolic process; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Malate dehydrogenase, NAD/NADP (InterPro:IPR010945), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), Malate dehydrogenase, NADP-dependent, plants (InterPro:IPR011273), NAD(P)-binding domain (InterPro:IPR016040), Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: Lactate/malate dehydrogenase family protein (TAIR:AT5G56720.1); Has 9958 Blast hits to 9954 proteins in 2609 species: Archae - 125; Bacteria - 6277; Metazoa - 781; Fungi - 166; Plants - 567; Viruses - 0; Other Eukaryotes - 2042 (source: NCBI BLink).
NP_851214.1
  • lactate/malate dehydrogenase family protein; FUNCTIONS IN: oxidoreductase activity, binding, malate dehydrogenase activity, catalytic activity, malate dehydrogenase (NADP+) activity; INVOLVED IN: oxidation reduction, malate metabolic process, carbohydrate metabolic process, metabolic process; LOCATED IN: in 6 components; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Malate dehydrogenase, NAD/NADP (InterPro:IPR010945), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), Malate dehydrogenase, NADP-dependent, plants (InterPro:IPR011273), NAD(P)-binding domain (InterPro:IPR016040), Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: Lactate/malate dehydrogenase family protein (TAIR:AT5G56720.1); Has 10000 Blast hits to 9996 proteins in 2628 species: Archae - 125; Bacteria - 6319; Metazoa - 780; Fungi - 166; Plants - 568; Viruses - 0; Other Eukaryotes - 2042 (source: NCBI BLink).
NP_974958.1
  • lactate/malate dehydrogenase family protein; FUNCTIONS IN: in 6 functions; INVOLVED IN: in 6 processes; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Malate dehydrogenase, NAD/NADP (InterPro:IPR010945), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), Malate dehydrogenase, NADP-dependent, plants (InterPro:IPR011273), NAD(P)-binding domain (InterPro:IPR016040), L-lactate/malate dehydrogenase (InterPro:IPR001557), Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: Lactate/malate dehydrogenase family protein (TAIR:AT5G56720.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23579722..23582395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125218.4 → NP_568875.2  lactate/malate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568875.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9YF37, A0A654GCA1, A0A7G2FI12
    Conserved Domains (1) summary
    PLN00112
    Location:1 → 442
    PLN00112; malate dehydrogenase (NADP); Provisional

  2. NM_180883.3 → NP_851214.1  lactate/malate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851214.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8H1E2, Q8LCQ9, Q8VXZ3, Q9LVL7
    UniProtKB/TrEMBL
    A0A7G2FJ35
    Conserved Domains (1) summary
    PLN00112
    Location:1 → 443
    PLN00112; malate dehydrogenase (NADP); Provisional

  3. NM_203229.2 → NP_974958.1  lactate/malate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974958.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UKK6, F4KEX3
    Conserved Domains (2) summary
    TIGR01759
    Location:1 → 310
    MalateDH-SF1; malate dehydrogenase
    cd01338
    Location:1 → 312
    MDH_choloroplast_like; Chloroplast-like malate dehydrogenases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8H1E2.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools