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CYP81F2 cytochrome P450, family 81, subfamily F, polypeptide 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835828, updated on 18-Sep-2024

Summary

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Official Symbol
CYP81F2
Official Full Name
cytochrome P450, family 81, subfamily F, polypeptide 2
Primary source
TAIR:AT5G57220
Locus tag
AT5G57220
See related
Araport:AT5G57220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
''cytochrome P450; cytochrome P450; family 81; MJB24.3; MJB24_3; polypeptide 2; polypeptide 2''; subfamily F
Summary
member of CYP81F, involved in glucosinolate metabolism. Mutants had impaired resistance to fungi.
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Genomic context

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See CYP81F2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (23187840..23189902)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene phosphatidylserine decarboxylase 2 Neighboring gene ENTH/ANTH/VHS superfamily protein Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene Thioredoxin superfamily protein Neighboring gene OSBP(oxysterol binding protein)-related protein 4C Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The gene controlling the indole glucosinolate modifier1 quantitative trait locus alters indole glucosinolate structures and aphid resistance in Arabidopsis. Pfalz M, et al. Plant Cell, 2009 Mar. PMID 19293369, Free PMC Article
  2. De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew. Hunziker P, et al. Plant Cell Environ, 2020 Jun. PMID 32275065
  3. A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense. Bednarek P, et al. Science, 2009 Jan 2. PMID 19095900
  4. Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101. van de Mortel JE, et al. Plant Physiol, 2012 Dec. PMID 23073694, Free PMC Article
  5. Glucosinolate metabolites required for an Arabidopsis innate immune response. Clay NK, et al. Science, 2009 Jan 2. PMID 19095898, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. study identifed CYP81F2 as the gene underlying Indole Glucosinolate Modifier1 (IGM1), a metabolic QTL for accumulation of 2 modified indole glucosinolates; also CYP81F2 contributes to defense against green peach aphid
    Title: The gene controlling the indole glucosinolate modifier1 quantitative trait locus alters indole glucosinolate structures and aphid resistance in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_125104.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to hypoxia IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within defense response by callose deposition in cell wall IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to fungus IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to insect IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within glucosinolate metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within indole glucosinolate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within indole glucosinolate metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within induced systemic resistance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
cytochrome P450, family 81, subfamily F, polypeptide 2
NP_200532.1
  • ''cytochrome P450, family 81, subfamily F, polypeptide 2'' (CYP81F2); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: in 7 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 81, subfamily F, polypeptide 3 (TAIR:AT4G37400.1); Has 35927 Blast hits to 35660 proteins in 1834 species: Archae - 77; Bacteria - 5490; Metazoa - 12066; Fungi - 7231; Plants - 9556; Viruses - 3; Other Eukaryotes - 1504 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23187840..23189902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125104.3 → NP_200532.1  cytochrome P450, family 81, subfamily F, polypeptide 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200532.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LVD6
    UniProtKB/TrEMBL
    A0A178UNW5, A0A5S9YF16, C3W7I0
    Conserved Domains (1) summary
    cd20653
    Location:62 → 476
    CYP81; cytochrome P450 family 81
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LVD6.1

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