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NMNAT nicotinate/nicotinamide mononucleotide adenyltransferase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835675, updated on 18-Sep-2024

Summary

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Official Symbol
NMNAT
Official Full Name
nicotinate/nicotinamide mononucleotide adenyltransferase
Primary source
TAIR:AT5G55810
Locus tag
AT5G55810
See related
Araport:AT5G55810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtNMNAT; MDF20.25; MDF20_25; nicotinate/nicotinamide mononucleotide adenyltransferase
Summary
encodes a bi-functional enzyme that expresses both nicotinamide-nucleotide adenylyltransferase (2.7.7.1) and nicotinate-nucleotide adenylyltransferase (2.7.7.18)activity.
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Genomic context

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See NMNAT in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Sequence:
Chromosome: 5; NC_003076.8 (22583972..22586405, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene inner centromere protein, ARK-binding region protein Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis thaliana nicotinate/nicotinamide mononucleotide adenyltransferase (AtNMNAT) is required for pollen tube growth. Hashida SN, et al. Plant J, 2007 Feb. PMID 17270012
  2. Arabidopsis J-protein J20 delivers the first enzyme of the plastidial isoprenoid pathway to protein quality control. Pulido P, et al. Plant Cell, 2013 Oct. PMID 24104567, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001203622.1
NM_001345151.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables nicotinamide-nucleotide adenylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nicotinate-nucleotide adenylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in NAD biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within NAD biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen tube growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
nicotinate/nicotinamide mononucleotide adenyltransferase
NP_001190551.1
  • nicotinate/nicotinamide mononucleotide adenyltransferase (NMNAT); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Probable nicotinate-nucleotide adenylyltransferase (InterPro:IPR005248), Cytidylyltransferase (InterPro:IPR004820).
NP_200392.3
  • nicotinate/nicotinamide mononucleotide adenyltransferase (NMNAT); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Probable nicotinate-nucleotide adenylyltransferase (InterPro:IPR005248), Cytidylyltransferase (InterPro:IPR004820); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    22583972..22586405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124963.5 → NP_200392.3  nicotinate/nicotinamide mononucleotide adenyltransferase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200392.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4K687, Q8VZB8, Q9FM58
    UniProtKB/TrEMBL
    A0A5S9YEI5
    Conserved Domains (1) summary
    PLN02945
    Location:1 → 235
    PLN02945; nicotinamide-nucleotide adenylyltransferase/nicotinate-nucleotide adenylyltransferase

  2. NM_001203622.1 → NP_001190551.1  nicotinate/nicotinamide mononucleotide adenyltransferase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190551.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654GBB6, F4K688
    Conserved Domains (1) summary
    cl00015
    Location:1 → 261
    nt_trans; nucleotidyl transferase superfamily

  3. NM_001345151.1 → NP_001329970.1  nicotinate/nicotinamide mononucleotide adenyltransferase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B9B6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4K687.1

Gene LinkOut

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