Tex16 testis expressed gene 16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tex16provided by MGI
Official Full Name: testis expressed gene 16provided by MGI
Primary source: MGI:MGI:1890545
See related: Ensembl:ENSMUSG00000079460 AllianceGenome:MGI:1890545
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4933403O08Rik
Summary: Predicted to enable U6 snRNA binding activity and pre-mRNA binding activity. Predicted to be part of Prp19 complex; U2-type catalytic step 1 spliceosome; and U2-type catalytic step 2 spliceosome. Orthologous to human TEX16P (testis expressed 16, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: X E1; X 48.76 cM

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (110804655..111159053)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (111896766..112127326)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tex16 is a gene that is expressed in testis that was identified in a genome-wide cDNA subtraction screen.
Title: An abundance of X-linked genes expressed in spermatogonia.
Germ-cell-specific sex-linked genes, like Tex16, are subject to meiotic sex-chromosome inactivation (MSCI) during spermatogenesis.
Title: Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.
Transcripts highly enriched in ovary; gene identified as candidate female fertility factor.
Title: Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G65218 (e-PCR)
- UniSTS:225886

G65792 (e-PCR)
- UniSTS:225928

D1S3696 (e-PCR)
- UniSTS:474274

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables U6 snRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info
enables pre-mRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
part_of Prp19 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type catalytic step 1 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of U2-type catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: testis expressed gene 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.