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DFL1 Auxin-responsive GH3 family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835539, updated on 18-Sep-2024

Summary

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Official Symbol
DFL1
Official Full Name
Auxin-responsive GH3 family protein
Primary source
TAIR:AT5G54510
Locus tag
AT5G54510
See related
Araport:AT5G54510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DWARF IN LIGHT 1; F24B18.13; F24B18_13; GH3.6; Gretchen Hagen3.6
Summary
Encodes an IAA-amido synthase that conjugates Ala, Asp, Phe, and Trp to auxin. Lines overexpressing this gene accumulate IAA-ASP and are hypersensitive to several auxins. Identified as a dominant mutation that displays shorter hypocotyls in light grown plants when compared to wild type siblings. Protein is similar to auxin inducible gene from pea (GH3).
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Genomic context

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See DFL1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (22130964..22133688, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pinoid-binding protein 1 Neighboring gene flavodoxin-like quinone reductase 1 Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene serine protease, putative (Protein of unknown function, DUF538)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DFL1, an auxin-responsive GH3 gene homologue, negatively regulates shoot cell elongation and lateral root formation, and positively regulates the light response of hypocotyl length. Nakazawa M, et al. Plant J, 2001 Jan. PMID 11169197
  2. Auxin controls Arabidopsis adventitious root initiation by regulating jasmonic acid homeostasis. Gutierrez L, et al. Plant Cell, 2012 Jun. PMID 22730403, Free PMC Article
  3. Characterization of an Arabidopsis enzyme family that conjugates amino acids to indole-3-acetic acid. Staswick PE, et al. Plant Cell, 2005 Feb. PMID 15659623, Free PMC Article
  4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_124831.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables indole-3-acetic acid amido synthetase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within auxin-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within intracellular auxin homeostasis TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to auxin IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Auxin-responsive GH3 family protein
NP_200262.1
  • DWARF IN LIGHT 1 (DFL1); FUNCTIONS IN: indole-3-acetic acid amido synthetase activity; INVOLVED IN: auxin homeostasis, response to auxin stimulus, auxin mediated signaling pathway, unidimensional cell growth; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: GH3 auxin-responsive promoter (InterPro:IPR004993); BEST Arabidopsis thaliana protein match is: Auxin-responsive GH3 family protein (TAIR:AT4G27260.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    22130964..22133688 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124831.3 → NP_200262.1  Auxin-responsive GH3 family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200262.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VYV6, Q9LSQ4
    UniProtKB/TrEMBL
    A0A178UBG0, A0A384LDF8, A0A7G2FG42, B5X4Z8
    Conserved Domains (1) summary
    PLN02620
    Location:1 → 612
    PLN02620; indole-3-acetic acid-amido synthetase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LSQ4.1

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