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CRR1 Dihydrodipicolinate reductase, bacterial/plant [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835286, updated on 18-Sep-2024

Summary

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Official Symbol
CRR1
Official Full Name
Dihydrodipicolinate reductase, bacterial/plant
Primary source
TAIR:AT5G52100
Locus tag
AT5G52100
See related
Araport:AT5G52100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
chlororespiration reduction 1; MSG15.20; MSG15_20
Summary
Is essential for chloroplast NAD(P)H dehydrogenase activity, which is involved in electron transfer between PSII and PSI. Likely functions in biogenesis or stabilization of the NAD(P)H dehydrogenase complex.
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Genomic context

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See CRR1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
10
Sequence:
Chromosome: 5; NC_003076.8 (21170048..21172346)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene chaperone (DUF2930) Neighboring gene ribonuclease H superfamily polynucleotidyl transferase Neighboring gene phloem protein 2-A14

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dihydrodipicolinate reductase-like protein, CRR1, is essential for chloroplast NAD(P)H dehydrogenase in Arabidopsis. Shimizu H, et al. Plant J, 2007 Nov. PMID 17727612
  2. Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways. Hudson AO, et al. Biochim Biophys Acta, 2005 Jan 18. PMID 15652176
  3. Multistep assembly of chloroplast NADH dehydrogenase-like subcomplex A requires several nucleus-encoded proteins, including CRR41 and CRR42, in Arabidopsis. Peng L, et al. Plant Cell, 2012 Jan. PMID 22274627, Free PMC Article
  4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results suggest that CRR1 is involved in biogenesis or stabilization of the NDH complex, possibly via the reduction of an unknown substrate
    Title: Dihydrodipicolinate reductase-like protein, CRR1, is essential for chloroplast NAD(P)H dehydrogenase in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

NM_124589.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 4-hydroxy-tetrahydrodipicolinate reductase IEA
Inferred from Electronic Annotation
more info
  
NOT enables 4-hydroxy-tetrahydrodipicolinate reductase IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in lysine biosynthetic process via diaminopimelate IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within photosynthesis, light reaction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Dihydrodipicolinate reductase, bacterial/plant
NP_200023.1
  • chlororespiration reduction 1 (crr1); FUNCTIONS IN: dihydrodipicolinate reductase activity; INVOLVED IN: photosynthesis, light reaction, lysine biosynthetic process via diaminopimelate; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dihydrodipicolinate reductase, C-terminal (InterPro:IPR022663), NAD(P)-binding domain (InterPro:IPR016040), Dihydrodipicolinate reductase, bacterial/plant (InterPro:IPR011770), Dihydrodipicolinate reductase, N-terminal (InterPro:IPR000846); Has 2708 Blast hits to 2708 proteins in 1059 species: Archae - 78; Bacteria - 2168; Metazoa - 0; Fungi - 0; Plants - 45; Viruses - 0; Other Eukaryotes - 417 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    21170048..21172346
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124589.3 → NP_200023.1  Dihydrodipicolinate reductase, bacterial/plant [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200023.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LG90, Q9FJ82
    UniProtKB/TrEMBL
    A0A178UH15, A0A5S9YDH6
    Conserved Domains (1) summary
    cl29298
    Location:34 → 298
    DapB_C; Dihydrodipicolinate reductase, C-terminus
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FJ82.1

Gene LinkOut

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