Intron maturase, type II family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Intron maturase, type II family protein
Primary source: TAIR:AT5G46920
Locus tag: AT5G46920
See related: Araport:AT5G46920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MQD22.6; MQD22_6
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 1

Sequence:: Chromosome: 5; NC_003076.8 (19053472..19056073)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The nMAT2 and PMH2 function in the splicing of similar subsets of group II introns. The proteins may serve as components of a proto-spliceosomal complex in Arabidopsis plant mitochondria.
Title: Analysis of the Roles of the Arabidopsis nMAT2 and PMH2 Proteins Provided with New Insights into the Regulation of Group II Intron Splicing in Land-Plant Mitochondria.
established the roles of one of these genes, At5g46920 (AtnMat2), in the splicing of several mitochondrial introns, including the single intron within cox2, nad1 intron2, and nad7 intron2.
Title: AtnMat2, a nuclear-encoded maturase required for splicing of group-II introns in Arabidopsis mitochondria.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_124063.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in Group II intron splicing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial mRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial mRNA processing	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrion organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
part_of ribonucleoprotein complex	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Intron maturase, type II family protein

NP_199503.1

Intron maturase, type II family protein; FUNCTIONS IN: RNA binding, RNA-directed DNA polymerase activity; INVOLVED IN: RNA-dependent DNA replication, RNA splicing; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Intron maturase, type II (InterPro:IPR000442), RNA-directed DNA polymerase (reverse transcriptase) (InterPro:IPR000477); BEST Arabidopsis thaliana protein match is: Intron maturase, type II family protein (TAIR:AT1G30010.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

19053472..19056073

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124063.3 → NP_199503.1 Intron maturase, type II family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_199503.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q94JV3, Q9FJR9

UniProtKB/TrEMBL

A0A178UPZ4, A0A5S9YBW1, A0A7G2FGA0

Conserved Domains (2) summary

cd01651
Location:183 → 460

RT_G2_intron; Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable element with ...

pfam01348
Location:540 → 583

Intron_maturas2; Type II intron maturase