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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834692, updated on 18-Sep-2024

Summary

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Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT5G46490
Locus tag
AT5G46490
See related
Araport:AT5G46490
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
K11I1.8; K11I1_8
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Genomic context

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Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (18850645..18853896)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene disease resistance protein (TIR-NBS-LRR class) family Neighboring gene protein VARIATION IN COMPOUND TRIGGERED ROOT growth protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
  2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001344686.1
NM_124019.1
NM_203165.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_568664.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G46260.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_974894.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, apoptosis, defense response, innate immune response; LOCATED IN: intrinsic to membrane; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G31540.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    18850645..18853896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001344681.1 → NP_001330257.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA82

  2. NM_001344682.1 → NP_001330258.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA65

  3. NM_001344683.1 → NP_001330254.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA95

  4. NM_001344684.1 → NP_001330255.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA80

  5. NM_001344685.1 → NP_001330259.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA95

  6. NM_203165.1 → NP_974894.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974894.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9FHF6
    Conserved Domains (6) summary
    smart00382
    Location:204 → 341
    AAA; ATPases associated with a variety of cellular activities
    sd00036
    Location:706 → 736
    LRR_3; leucine-rich repeat [structural motif]
    pfam01582
    Location:12 → 174
    TIR; TIR domain
    pfam07725
    Location:669 → 687
    LRR_3; Leucine Rich Repeat
    pfam13191
    Location:182 → 230
    AAA_16; AAA ATPase domain
    pfam13306
    Location:703 → 796
    LRR_5; Leucine rich repeats (6 copies)

  7. NM_001344686.1 → NP_001330256.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BA91

  8. NM_124019.1 → NP_568664.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568664.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93ZC0
    Conserved Domains (3) summary
    smart00382
    Location:204 → 346
    AAA; ATPases associated with a variety of cellular activities
    pfam01582
    Location:12 → 174
    TIR; TIR domain
    pfam13191
    Location:182 → 230
    AAA_16; AAA ATPase domain
Nucleotide Protein
Heading Accession and Version

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