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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834688, updated on 18-Sep-2024

Summary

Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT5G46450
Locus tag
AT5G46450
See related
Araport:AT5G46450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
K11I1.4; K11I1_4
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Genomic context

Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (18835605..18840058)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L32e Neighboring gene ncRNA Neighboring gene PPR containing-like protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene disease resistance protein (TIR-NBS-LRR class) family

General gene information

NM_001344679.1
NM_001344680.1
NM_124015.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_199457.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G46470.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    18835605..18840058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124015.2NP_199457.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199457.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654G8K7, Q9FHG0
    Conserved Domains (7) summary
    cd09293
    Location:626714
    AMN1; Antagonist of mitotic exit network protein 1
    PLN03210
    Location:11123
    PLN03210; Resistant to P. syringae 6; Provisional
    sd00033
    Location:607629
    LRR_RI; leucine-rich repeat [structural motif]
    pfam01582
    Location:13178
    TIR; TIR domain
    pfam07725
    Location:606624
    LRR_3; Leucine Rich Repeat
    pfam13191
    Location:185234
    AAA_16; AAA ATPase domain
    cl17190
    Location:212242
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  2. NM_001344679.1NP_001332185.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BG45, A0A654G8K7
  3. NM_001344680.1NP_001332184.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BGA7, A0A654G8K7