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PDLP1 plasmodesmata-located protein 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834421, updated on 18-Sep-2024

Summary

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Official Symbol
PDLP1
Official Full Name
plasmodesmata-located protein 1
Primary source
TAIR:AT5G43980
Locus tag
AT5G43980
See related
Araport:AT5G43980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MRH10.9; MRH10_9; PDLP1A; plasmodesmata-located protein 1; PLASMODESMATA-LOCATED PROTEIN 1A
Summary
Encodes a plasmodesmal protein that affects the intercellular movement of molecules through the plasmodesmata. The cytoplasmic C-terminal portion of the protein is connected to the apoplastic N-terminal portion of the protein by a single transmembrane domain (TMD). It is transported to the plasmodesmata through the secretory pathway. PDLP1 has two DUF26 domains and a signal peptide, but the proper localization of the protein appears to depend on the TMD.
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Genomic context

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See PDLP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (17694680..17696690, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein Neighboring gene translocase of outer membrane 22-V Neighboring gene SET-domain containing protein lysine methyltransferase family protein Neighboring gene Glutathione S-transferase family protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants. Lim GH, et al. Cell Host Microbe, 2016 Apr 13. PMID 27078071
  2. Plasmodesmata-located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long-distance movement of Defective in Induced Resistance1 in Arabidopsis. Carella P, et al. Plant Biol (Stuttg), 2015 Mar. PMID 25296648
  3. A family of plasmodesmal proteins with receptor-like properties for plant viral movement proteins. Amari K, et al. PLoS Pathog, 2010 Sep 23. PMID 20886105, Free PMC Article
  4. Specific targeting of a plasmodesmal protein affecting cell-to-cell communication. Thomas CL, et al. PLoS Biol, 2008 Jan. PMID 18215111, Free PMC Article
  5. The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. Caillaud MC, et al. PLoS Pathog, 2014 Oct. PMID 25393742, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Plasmodesmata localizing proteins PDLP1 and PDLP5 are required for systemic acquired resistance.
    Title: Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants.
  2. The pdlp1,2,3 triple mutant is more susceptible to Hyaloperonospora arabidopsidis (Hpa) while overexpression of PDLP1 enhances plant resistance, suggesting that PDLPs enhance basal immunity against Hpa.
    Title: The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition.
  3. PDLP1 plays role in systemic acquired resistance and the long-distance movement of DIR1 protein in Arabidopsis.
    Title: Plasmodesmata-located protein overexpression negatively impacts the manifestation of systemic acquired resistance and the long-distance movement of Defective in Induced Resistance1 in Arabidopsis.
  4. PDLP1a is targeted to plasmodesmata via the secretory pathway in a Brefeldin A-sensitive and COPII-dependent manner
    Title: Specific targeting of a plasmodesmal protein affecting cell-to-cell communication.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_123765.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within plasmodesmata-mediated intercellular transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within transport of virus in multicellular host IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in plant-type cell wall HDA PubMed 
located_in plasmodesma HDA PubMed 
located_in plasmodesma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
plasmodesmata-located protein 1
NP_199211.2
  • plasmodesmata-located protein 1 (PDLP1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF26 (InterPro:IPR002902); BEST Arabidopsis thaliana protein match is: plasmodesmata-located protein 3 (TAIR:AT2G33330.1); Has 956 Blast hits to 914 proteins in 25 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 956; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    17694680..17696690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123765.3 → NP_199211.2  plasmodesmata-located protein 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199211.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GXV7, Q9FNC8
    UniProtKB/TrEMBL
    A0A5S9YAQ3, A0A654G7S3
    Conserved Domains (1) summary
    pfam01657
    Location:32 → 132
    Stress-antifung; Salt stress response/antifungal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GXV7.2

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