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CLH2 chlorophyllase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834408, updated on 18-Sep-2024

Summary

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Official Symbol
CLH2
Official Full Name
chlorophyllase 2
Primary source
TAIR:AT5G43860
Locus tag
AT5G43860
See related
Araport:AT5G43860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA CHLOROPHYLLASE 2; ATCLH2; chlorophyllase 2; MQD19.22; MQD19_22
Summary
Encodes a chlorophyllase, the first enzyme in chlorophyll degradation. It catalyzes the hydrolysis of the ester bond to chlorophyllide and phytol. AtCLH2 has a typical signal sequence for the chloroplast. Gene expression does not respond to methyljasmonate, a known promoter of senescence and chlorophyll degradation.
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Genomic context

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See CLH2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (17630426..17632338)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor A6A Neighboring gene RmlC-like cupins superfamily protein Neighboring gene auxin canalization protein (DUF828) Neighboring gene methyl-coenzyme M reductase II subunit gamma, putative (DUF3741) Neighboring gene Flavin-binding monooxygenase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Subcellular localization of chlorophyllase2 reveals it is not involved in chlorophyll degradation during senescence in Arabidopsis thaliana. Hu X, et al. Plant Sci, 2020 Jan. PMID 31779896
  2. Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled. Banas AK, et al. Plant Physiol, 2011 Nov. PMID 21896889, Free PMC Article
  3. Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence. Zhou X, et al. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao, 2007 Dec. PMID 18349515
  4. The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana. Schenk N, et al. FEBS Lett, 2007 Nov 27. PMID 17996203
  5. Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants. Kariola T, et al. Plant Cell, 2005 Jan. PMID 15598807, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Based on the collective data, the authors conclude that CLH2 is not involved in Chl breakdown during senescence in Arabidopsis.
    Title: Subcellular localization of chlorophyllase2 reveals it is not involved in chlorophyll degradation during senescence in Arabidopsis thaliana.
  2. The levels of mRNA of two enzymes involved in chlorophyll catabolism in Arabidopsis, products of two chlorophyllase genes, AtCLH1 and AtCLH2, dramatically increase upon illumination with white light.
    Title: Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled.
  3. Data conclude that AtCLH2 might be required at the initial stage of leaf senescence, quite likely playing a role in converting Chl b to a.
    Title: Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence.
  4. AtCLHs are not required for senescence-related chlorophyll breakdown in vivo and propose that genuine chlorophyllase has not yet been molecularly identified
    Title: The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana.
  5. We propose that AtCLH1 is involved in plant damage control and can modulate the balance between different plant defense pathways.
    Title: Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants.
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Pathways from PubChem

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General gene information

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NM_123753.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables chlorophyllase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables chlorophyllase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chlorophyll catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chlorophyll catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
chlorophyllase 2
NP_199199.1
  • chlorophyllase 2 (CLH2); CONTAINS InterPro DOMAIN/s: Chlorophyllase-like (InterPro:IPR010821), Chlorophyllase, chloroplast (InterPro:IPR017395); BEST Arabidopsis thaliana protein match is: chlorophyllase 1 (TAIR:AT1G19670.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    17630426..17632338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123753.3 → NP_199199.1  chlorophyllase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199199.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M7I7
    UniProtKB/TrEMBL
    A0A178UA51, A0A5S9YBV0, A0A654G7T3
    Conserved Domains (1) summary
    PLN00021
    Location:1 → 318
    PLN00021; chlorophyllase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M7I7.1

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