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TOPP6 type one serine/threonine protein phosphatase 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834356, updated on 18-Sep-2024

Summary

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Official Symbol
TOPP6
Official Full Name
type one serine/threonine protein phosphatase 6
Primary source
TAIR:AT5G43380
Locus tag
AT5G43380
See related
Araport:AT5G43380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
type one serine/threonine protein phosphatase 6
Summary
encodes a type I serine/threonine protein phosphatase expressed in expressed in roots, rosettes and flowers.
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Genomic context

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See TOPP6 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (17419790..17421982, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene phosphate transporter 1;3 Neighboring gene phosphate transporter 2 Neighboring gene plant/protein Neighboring gene plant/protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning and chromosomal mapping of type one serine/threonine protein phosphatases in Arabidopsis thaliana. Lin Q, et al. Plant Mol Biol, 1998 Jun. PMID 9617814
  2. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
  3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001036923.1
NM_123704.3
NM_180792.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein dephosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
type one serine/threonine protein phosphatase 6
NP_001032000.1
  • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 7210 Blast hits to 7010 proteins in 618 species: Archae - 78; Bacteria - 522; Metazoa - 2407; Fungi - 1451; Plants - 977; Viruses - 15; Other Eukaryotes - 1760 (source: NCBI BLink).
NP_568625.1
  • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_851123.1
  • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 7151 Blast hits to 6957 proteins in 613 species: Archae - 78; Bacteria - 520; Metazoa - 2406; Fungi - 1417; Plants - 983; Viruses - 15; Other Eukaryotes - 1732 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    17419790..17421982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180792.3 → NP_851123.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851123.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O48641, O82733, Q2V319, Q8L761
    UniProtKB/TrEMBL
    A0A5S9YAM6
    Conserved Domains (2) summary
    PTZ00480
    Location:6 → 297
    PTZ00480; serine/threonine-protein phosphatase; Provisional
    cd07414
    Location:6 → 293
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

  2. NM_123704.3 → NP_568625.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568625.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178URQ1
    Conserved Domains (2) summary
    PTZ00480
    Location:6 → 297
    PTZ00480; serine/threonine-protein phosphatase; Provisional
    cd07414
    Location:6 → 293
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

  3. NM_001036923.1 → NP_001032000.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001032000.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178URQ1
    Conserved Domains (2) summary
    PTZ00480
    Location:6 → 297
    PTZ00480; serine/threonine-protein phosphatase; Provisional
    cd07414
    Location:6 → 293
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O82733.3

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