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c-NAD-MDH2 Lactate/malate dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834351, updated on 18-Sep-2024

Summary

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Official Symbol
c-NAD-MDH2
Official Full Name
Lactate/malate dehydrogenase family protein
Primary source
TAIR:AT5G43330
Locus tag
AT5G43330
See related
Araport:AT5G43330
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cytosolic-NAD-dependent malate dehydrogenase 2; MWF20.2; MWF20_2
Summary
predicted to encode a cytosolic malate dehydrogenase.
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Genomic context

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See c-NAD-MDH2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
7
Sequence:
Chromosome: 5; NC_003076.8 (17390381..17392741)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene COP1-interacting protein-like protein Neighboring gene casein kinase I-like 8 Neighboring gene phosphate transporter 1;6 Neighboring gene phosphate transporter 1;1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling. Liszka A, et al. Biochem J, 2020 Oct 16. PMID 32897311, Free PMC Article
  2. Determining novel functions of Arabidopsis 14-3-3 proteins in central metabolic processes. Diaz C, et al. BMC Syst Biol, 2011 Nov 21. PMID 22104211, Free PMC Article
  3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
  4. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
  5. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling.
    Title: Three cytosolic NAD-malate dehydrogenase isoforms of Arabidopsis thaliana: on the crossroad between energy fluxes and redox signaling.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_123699.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables L-malate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in malate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 
located_in plastid HDA PubMed 

General protein information

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Preferred Names
Lactate/malate dehydrogenase family protein
NP_199147.1
  • Lactate/malate dehydrogenase family protein; FUNCTIONS IN: in 6 functions; INVOLVED IN: in 6 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Malate dehydrogenase, NAD-dependent, cytosolic (InterPro:IPR011274), Lactate/malate dehydrogenase, N-terminal (InterPro:IPR001236), Malate dehydrogenase, NAD/NADP (InterPro:IPR010945), Lactate/malate dehydrogenase, C-terminal (InterPro:IPR022383), NAD(P)-binding domain (InterPro:IPR016040), L-lactate/malate dehydrogenase (InterPro:IPR001557), Malate dehydrogenase, active site (InterPro:IPR001252), Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (InterPro:IPR015955); BEST Arabidopsis thaliana protein match is: Lactate/malate dehydrogenase family protein (TAIR:AT1G04410.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    17390381..17392741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123699.4 → NP_199147.1  Lactate/malate dehydrogenase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199147.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P57106, Q8LA78, Q9LSX3
    UniProtKB/TrEMBL
    A0A178UFW3, A0A5S9YBP6
    Conserved Domains (2) summary
    cd01336
    Location:4 → 328
    MDH_cytoplasmic_cytosolic; Cytoplasmic and cytosolic Malate dehydrogenases
    PLN00135
    Location:24 → 332
    PLN00135; malate dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P57106.1

Gene LinkOut

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